[HTML][HTML] Erlotinib in lung cancer—molecular and clinical predictors of outcome

MS Tsao, A Sakurada, JC Cutz, CQ Zhu… - … England Journal of …, 2005 - Mass Medical Soc
… benefit from erlotinib. To clarify the role of EGFR in the outcome of non–small-cell lung cancer,
we … of EGFR, and mutation status of the gene in a subgroup of patients in the BR.21 study. …

[HTML][HTML] Erlotinib in previously treated non–small-cell lung cancer

FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
… to determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs
survival in non–small-cell lung cancer after the failure of first-line or second-line chemotherapy. …

Erlotinib: a new therapeutic approach for non-small cell lung cancer

P Bonomi - Expert opinion on investigational drugs, 2003 - Taylor & Francis
… Although treatment with cytotoxic agents has produced modest survival improvement in
patients with stage III and IV non-small cell lung cancer (NSCLC), it appears that a plateau has …

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… Symptom improvement in lung cancer patients treated with erlotinib: quality of life
analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. …

First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial

SM Lee, I Khan, S Upadhyay, C Lewanski… - The lancet …, 2012 - thelancet.com
… We investigated whether erlotinib improves clinical outcome in these patients. … patients to
receive erlotinib and 320 to receive placebo. We followed up patients until March 31, 2011. 657 …

Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
erlotinib for non-small cell lung cancer (NSCLC), we performed a population-based observational
study. The study involved 307 patients treated with erlotinib … The tumor response and …

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
… phase II trial, the efficacy and safety of gefitinib and erlotinib was evaluated as the second-line
therapy for advanced non-small cell lung cancer (NSCLC). Patients and methods …

Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer

JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
… on 4068 concentration samples from 1047 patients receiving erlotinib as a single agent or in
erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …

[PDF][PDF] Determinants of tumor response and survival with erlotinib in patients with non—small-cell lung cancer

R Pérez-Soler, A Chachoua, LA Hammond… - Journal of clinical …, 2004 - researchgate.net
… This phase II study of erlotinib in patients with HER1/EGFR-expressing non–small-cell lung
cancer previously treated with platinum-based chemotherapy evaluated tumor response, …

The role of erlotinib (Tarceva, OSI 774) in the treatment of non-small cell lung cancer

R Perez-Soler - Clinical cancer research, 2004 - AACR
Erlotinib (Tarceva) is a reversible and highly specific inhibitor … of 57 patients with EGFR-positive
non-small cell lung cancer … in 50 patients with bronchoalveolar carcinoma has shown a …