[HTML][HTML] Erlotinib in lung cancer—molecular and clinical predictors of outcome
… benefit from erlotinib. To clarify the role of EGFR in the outcome of non–small-cell lung cancer,
we … of EGFR, and mutation status of the gene in a subgroup of patients in the BR.21 study. …
we … of EGFR, and mutation status of the gene in a subgroup of patients in the BR.21 study. …
[HTML][HTML] Erlotinib in previously treated non–small-cell lung cancer
FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
… to determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs
survival in non–small-cell lung cancer after the failure of first-line or second-line chemotherapy. …
survival in non–small-cell lung cancer after the failure of first-line or second-line chemotherapy. …
Erlotinib: a new therapeutic approach for non-small cell lung cancer
P Bonomi - Expert opinion on investigational drugs, 2003 - Taylor & Francis
… Although treatment with cytotoxic agents has produced modest survival improvement in
patients with stage III and IV non-small cell lung cancer (NSCLC), it appears that a plateau has …
patients with stage III and IV non-small cell lung cancer (NSCLC), it appears that a plateau has …
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… Symptom improvement in lung cancer patients treated with erlotinib: quality of life
analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. …
analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. …
First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
SM Lee, I Khan, S Upadhyay, C Lewanski… - The lancet …, 2012 - thelancet.com
… We investigated whether erlotinib improves clinical outcome in these patients. … patients to
receive erlotinib and 320 to receive placebo. We followed up patients until March 31, 2011. 657 …
receive erlotinib and 320 to receive placebo. We followed up patients until March 31, 2011. 657 …
Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer
T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
… erlotinib for non-small cell lung cancer (NSCLC), we performed a population-based observational
study. The study involved 307 patients treated with erlotinib … The tumor response and …
study. The study involved 307 patients treated with erlotinib … The tumor response and …
Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
… phase II trial, the efficacy and safety of gefitinib and erlotinib was evaluated as the second-line
therapy for advanced non-small cell lung cancer (NSCLC). Patients and methods …
therapy for advanced non-small cell lung cancer (NSCLC). Patients and methods …
Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer
JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
… on 4068 concentration samples from 1047 patients receiving erlotinib as a single agent or in
… erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …
… erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …
[PDF][PDF] Determinants of tumor response and survival with erlotinib in patients with non—small-cell lung cancer
R Pérez-Soler, A Chachoua, LA Hammond… - Journal of clinical …, 2004 - researchgate.net
… This phase II study of erlotinib in patients with HER1/EGFR-expressing non–small-cell lung
cancer previously treated with platinum-based chemotherapy evaluated tumor response, …
cancer previously treated with platinum-based chemotherapy evaluated tumor response, …
The role of erlotinib (Tarceva, OSI 774) in the treatment of non-small cell lung cancer
R Perez-Soler - Clinical cancer research, 2004 - AACR
… Erlotinib (Tarceva) is a reversible and highly specific inhibitor … of 57 patients with EGFR-positive
non-small cell lung cancer … in 50 patients with bronchoalveolar carcinoma has shown a …
non-small cell lung cancer … in 50 patients with bronchoalveolar carcinoma has shown a …
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