[HTML][HTML] Side-effects of long-term administration of erlotinib in patients with non-small cell lung cancer

A Becker, A van Wijk, EF Smit, PE Postmus - Journal of Thoracic Oncology, 2010 - Elsevier
patients receiving erlotinib for adenocarcinoma in the lung. … good tumor response on this
EGFR TKI treatment, patients and … discontinuation and subsequently lung cancer progression. …

Tumor response and toxicity of neoadjuvant erlotinib in patients with early-stage non–small-cell lung cancer

EE Schaake, I Kappers, HE Codrington… - Journal of clinical …, 2012 - ascopubs.org
… A minority of patients with non–small-cell lung cancer (NSCLC) present with localized
disease. Treatment for early-stage disease in fit patients is focused on curative surgery. …

Retrospective study of erlotinib in patients with advanced squamous lung cancer

JS Tseng, TY Yang, KC Chen, KH Hsu, HY Chen… - Lung Cancer, 2012 - Elsevier
… low in lung SCC. The aim of this study was to evaluate the status … erlotinib treatment and
EGFR mutation in lung SCC patients. Methods: We retrospectively enrolled lung cancer patients

SELECT: a phase II trial of adjuvant erlotinib in patients with resected epidermal growth factor receptor–mutant non–small-cell lung cancer

NA Pennell, JW Neal, JE Chaft, CG Azzoli… - Journal of Clinical …, 2019 - ascopubs.org
… Given the pivotal role of epidermal growth factor receptor (EGFR) inhibitors in advanced
EGFR-mutant non–small-cell lung cancer (NSCLC), we tested adjuvant erlotinib in patients with …

First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial

SM Lee, I Khan, S Upadhyay, C Lewanski… - The lancet …, 2012 - thelancet.com
… We investigated whether erlotinib improves clinical outcome in these patients. … patients to
receive erlotinib and 320 to receive placebo. We followed up patients until March 31, 2011. 657 …

Influence of the acidic beverage cola on the absorption of erlotinib in patients with non–small-cell lung cancer

RWF van Leeuwen, R Peric… - Journal of Clinical …, 2016 - ascopubs.org
Patients and Methods In this randomized, cross-over, pharmacokinetic study in patients with
non–small-cell lung cancer… day period of concomitant treatment with erlotinib, with or without …

Phase III trial of vandetanib compared with erlotinib in patients with previously treated advanced non–small-cell lung cancer

RB Natale, S Thongprasert, FA Greco… - Journal of Clinical …, 2011 - ascopubs.org
… This phase III study assessed the efficacy of vandetanib versus erlotinib in unselected patients
with advanced non–small-cell lung cancer (NSCLC) after treatment failure with one to two …

Dacomitinib versus erlotinib in patients with advanced-stage, previously treated non-small-cell lung cancer (ARCHER 1009): a randomised, double-blind, phase 3 trial

SS Ramalingam, PA Jänne, T Mok, K O'Byrne… - The lancet …, 2014 - thelancet.com
… On the basis of these findings, we did a randomised phase 3 trial to compare dacomitinib
with erlotinib in patients with advanced non-small-cell lung cancer, including patients with …

… (CT) in advanced non-small cell lung cancer (NSCLC) patients (p) with epidermal growth factor receptor (EGFR) mutations: Interim results of the European Erlotinib …

…, LG Paz-Ares, Spanish Lung Cancer Group - Journal of clinical …, 2011 - ascopubs.org
… efficacy and safety profile of erlotinib compares with CT in … phase III study comparing erlotinib
with platinum-based CT in … and 174 patients were randomly assigned to receive erlotinib or …

… -controlled trial of erlotinib in patients with advanced non-small cell lung cancer (NSCLC) following failure of 1st line or 2nd line chemotherapy. A National Cancer …

FA Shepherd, J Pereira, TE Ciuleanu… - Journal of Clinical …, 2004 - ascopubs.org
… , time to deterioration of patient reported symptoms (TTDS), … patients randomized to erlotinib.
Rash and diarrhea were the most frequent symptoms; 5% of patients discontinued erlotinib