A phase II trial of erlotinib in patients with EGFR wild-type advanced non-small-cell lung cancer

T Kobayashi, T Koizumi, T Agatsuma, M Yasuo… - Cancer chemotherapy …, 2012 - Springer
… NSCLC patients. In addition, several clinical studies indicated that erlotinib could confer
benefits in certain patients with NSCLC after gefitinib failure [18, 19]. Thus, erlotinib may have a …

… growth factor receptor expression as predictors of survival benefit from erlotinib for patients with non–small-cell lung cancer in the National Cancer Institute of Canada …

GM Clark, DM Zborowski, P Santabárbara, K Ding… - Clinical lung cancer, 2006 - Elsevier
… for men and patients with squamous cell histology. … cell non–small-cell lung cancer derived
a significant survival benefit from erlotinib (HR, 0.66; P = 0.015) despite a very low tumor

Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study

G Giaccone, M Gallegos Ruiz, T Le Chevalier… - Clinical Cancer …, 2006 - AACR
… Purpose: Erlotinib has proven activity in pretreated patients with advanced non–small cell
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …

[HTML][HTML] Examining treatment outcomes with Erlotinib in patients with advanced non–small cell lung cancer whose Tumors Harbor uncommon EGFR mutations

B Klughammer, W Brugger, F Cappuzzo… - Journal of Thoracic …, 2016 - Elsevier
… (TKI) erlotinib has been at the forefront of changes in treatment practice for advanced non–small
cell lung cancer (NSCLC) over the past 10 years. Erlotinib was initially approved for use …

[HTML][HTML] Phase I results from a study of crizotinib in combination with erlotinib in patients with advanced nonsquamous non–small cell lung cancer

SHI Ou, R Govindan, KD Eaton, GA Otterson… - Journal of Thoracic …, 2017 - Elsevier
… The MTD of the combination of crizotinib and erlotinib in patients with advanced NSCLC
was crizotinib, 150 mg twice daily, with erlotinib, 100 mg once daily, which is less than the …

[HTML][HTML] Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
erlotinib for non-small cell lung cancer (NSCLC), we performed a population-based observational
study. The study involved 307 patients treated with erlotinib … The tumor response and …

A phase I/II study of weekly high‐dose erlotinib in previously treated patients with nonsmall cell lung cancer

DT Milton, CG Azzoli, RT Heelan… - Cancer …, 2006 - Wiley Online Library
… Preclinical studies have suggested that erlotinib at high doses may inhibit additional …
erlotinib administered on a weekly schedule to patients with advanced nonsmall cell lung cancer

Clinical efficacy of erlotinib in patients previously treated for advanced non‐small cell lung cancer

S Zhou, S Ren, L Yan, L Zhang, L Tang, J Zhang… - …, 2009 - Wiley Online Library
… objective: Erlotinib is one of the standard second/third line treatments for patients with
advanced non-small cell lung cancer (NSCLC). This study investigated the efficacy of erlotinib in a …

[HTML][HTML] Dacomitinib versus erlotinib in patients with EGFR-mutated advanced nonsmall-cell lung cancer (NSCLC): pooled subset analyses from two randomized trials

SS Ramalingam, K O'Byrne, M Boyer, T Mok… - Annals of …, 2016 - Elsevier
… nonsmall-cell lung cancer (NSCLC), dacomitinib showed improved PFS compared with
erlotinib in … This led to a phase III study of dacomitinib versus erlotinib in patients with advanced …

A phase II pharmacodynamic study of erlotinib in patients with advanced non–small cell lung cancer previously treated with platinum-based chemotherapy

E Felip, F Rojo, M Reck, A Heller, B Klughammer… - Clinical Cancer …, 2008 - AACR
Erlotinib, an epidermal growth factor receptor (EGFR) … in unselected patients with advanced
non–small cell lung cancer (… predict which patients will obtain clinical benefit from erlotinib. …