Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non–small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial

K Kelly, NK Altorki, WEE Eberhardt… - Journal of Clinical …, 2015 - escholarship.org
… Epidermal growth factor receptor (EGFR) –tyrosine kinase inhibitors have proven efficacy
in advanced non–small-cell lung cancer (NSCLC). We hypothesized that erlotinib would be …

The effectiveness of erlotinib against brain metastases in non-small cell lung cancer patients

H Bai, B Han - American journal of clinical oncology, 2013 - journals.lww.com
… in non–small cell lung cancer (NSCLC), and patient prognosis is poor. Erlotinib, a specific
inhibitor of … This study evaluates erlotinib in the treatment for brain metastases from NSCLC. …

Randomized phase II trial of erlotinib or standard chemotherapy in patients with advanced non–small-cell lung cancer and a performance status of 2

R Lilenbaum, R Axelrod, S Thomas… - Journal of Clinical …, 2008 - ascopubs.org
Patients who crossed over to erlotinib had a median survival of 14.9 months. Sex, histology,
… outcome with erlotinib. Rash and diarrhea were more common with erlotinib; emesis, …

Eye, hepatobiliary, and renal disorders of erlotinib in patients with non-small-cell lung cancer: A meta-analysis

HD Choi, MJ Chang - PloS one, 2020 - journals.plos.org
Erlotinib is an epidermal growth factor receptor (EGFR) … -cell lung cancer (NSCLC). Skin
rash and diarrhea are well-known and common adverse events in patients receiving erlotinib, …

Erlotinib in the first-line treatment of non-small-cell lung cancer

M D'Arcangelo, F Cappuzzo - Expert review of anticancer therapy, 2013 - Taylor & Francis
… Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer
harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, …

Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive non–small cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
… First-line gefitinib for patients with advanced non–small-cell lung cancer harboring … First-line
gefitinib for patients with advanced non–small-cell lung cancer harboring epidermal growth …

A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - … journal of cancer, 2017 - nature.com
… A phase III trial was conducted to compare the safety and efficacy of erlotinib with that of
gefitinib in advanced non-small cell lung cancer harbouring epidermal growth factor receptor …

[HTML][HTML] First-line erlotinib versus gemcitabine/cisplatin in patients with advanced EGFR mutation-positive non-small-cell lung cancer: analyses from the phase III …

YL Wu, C Zhou, CK Liam, G Wu, X Liu, Z Zhong, S Lu… - Annals of oncology, 2015 - Elsevier
Patients were stratified by EGFR mutation type, ECOG PS, gender, and country. … , erlotinib
patients could crossover to receive GP and GP patients could crossover to receive erlotinib. All …

Erlotinib, cabozantinib, or erlotinib plus cabozantinib as second-line or third-line treatment of patients with EGFR wild-type advanced non-small-cell lung cancer  …

JW Neal, SE Dahlberg, HA Wakelee, SC Aisner… - The lancet …, 2016 - thelancet.com
… with advanced non-small-cell lung cancer (… lung cancer tumorigenesis. We compared the
efficacy of cabozantinib alone or in combination with erlotinib versus erlotinib alone in patients

[HTML][HTML] … growth factor receptor-related tumor markers and clinical outcomes with erlotinib in non-small cell lung cancer: an analysis of patients from german centers in …

CP Schneider, D Heigener, K Schott-von-Römer… - Journal of Thoracic …, 2008 - Elsevier
tumor growth and progression in many cancers1, 2 and EGFR overexpression occurs in up
to 80% of non-small cell lung cancers (NSCLC).3, 4 Erlotinibpatients with relapsed NSCLC. …