Phase II study of erlotinib in advanced non–small-cell lung cancer after failure of gefitinib
BC Cho, CK Im, MS Park, SK Kim, J Chang… - Journal of clinical …, 2007 - ascopubs.org
… gefitinib therapy according to response to erlotinib, it was significantly longer in patients who
showed PR/SD on erlotinib than in patients who did not (279 v 111 days in patients without …
showed PR/SD on erlotinib than in patients who did not (279 v 111 days in patients without …
[HTML][HTML] Phase II study of erlotinib as a salvage treatment for non-small-cell lung cancer patients after failure of gefitinib treatment
DH Lee, SW Kim, C Suh, DH Yoon, EJ Yi, JS Lee - Annals of oncology, 2008 - Elsevier
… suggested that erlotinib should not be given routinely after failure of gefitinib treatment, but
… subset of patients, especially those who had already benefited from prior gefitinib treatment. …
… subset of patients, especially those who had already benefited from prior gefitinib treatment. …
Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
… gefitinib and erlotinib in an enriched patient … of gefitinib or erlotinib independently compared
to a historical control as the second-line therapy in patients with NSCLC who have failed …
to a historical control as the second-line therapy in patients with NSCLC who have failed …
Comparison of gefitinib versus erlotinib in patients with nonsmall cell lung cancer who failed previous chemotherapy
… between gefitinib-treated and erlotinib-treated patients with NSCLC who had failed prior
chemotherapy. Our analysis shows that gefitinib and erlotinib in pretreated patients with …
chemotherapy. Our analysis shows that gefitinib and erlotinib in pretreated patients with …
[HTML][HTML] Erlotinib after failure of gefitinib in patients with advanced non-small cell lung cancer previously responding to gefitinib
… Erlotinib seems to be a potential therapeutic option for treatment of selected advanced NSCLC
patients after failure of gefitinib. … clarify how to select patients for treatment with epidermal …
patients after failure of gefitinib. … clarify how to select patients for treatment with epidermal …
Erlotinib in advanced non-small-cell lung cancer after gefitinib failure
ZT Zhou, XH Xu, Q Wei, M Lu, J Wang… - Cancer chemotherapy and …, 2009 - Springer
… In our study, The DCR of erlotinib after gefitinib failure was similar to that in Cho’s study.
Most patients who benefit from erlotinib had also benefited from prior gefitinib treatment, but we …
Most patients who benefit from erlotinib had also benefited from prior gefitinib treatment, but we …
Pooled analysis of the reports of erlotinib after failure of gefitinib for non-small cell lung cancer
K Kaira, T Naito, T Takahashi, E Ayabe, R Shimoyama… - Lung Cancer, 2010 - Elsevier
… patients who receive erlotinib after gefitinib failure revealed that erlotinib may produce clinical
benefits in patients … than 6 months) for prior gefitinib therapy. Moreover, EGFR mutations …
benefits in patients … than 6 months) for prior gefitinib therapy. Moreover, EGFR mutations …
The administration of gefitinib in patients with advanced non-small-cell lung cancer after the failure of erlotinib
F Grossi, E Rijavec, MG Dal Bello, C Defferrari… - Cancer chemotherapy …, 2012 - Springer
… gefitinib, particularly in patients in whom the disease had been stabilized for a long time prior
to gefitinib … toxicity of gefitinib in patients whose disease progressed after erlotinib therapy. …
to gefitinib … toxicity of gefitinib in patients whose disease progressed after erlotinib therapy. …
[HTML][HTML] Clinical efficacy of erlotinib, a salvage treatment for non-small cell lung cancer patients following gefitinib failure
… In conclusion, when rechallenging with the EGFR TKI erlotinib following gefitinib failure,
patients who showed prolonged PFS with gefitinib may benefit from erlotinib treatment. Further …
patients who showed prolonged PFS with gefitinib may benefit from erlotinib treatment. Further …
Erlotinib after gefitinib failure in relapsed non-small cell lung cancer: clinical benefit with optimal patient selection
A Hata, N Katakami, H Yoshioka, S Fujita, K Kunimasa… - Lung cancer, 2011 - Elsevier
… Between January 2008 and October 2009, we analyzed 125 patients with relapsed
NSCLC who had received erlotinib therapy after gefitinib failure at our institutes. Results were …
NSCLC who had received erlotinib therapy after gefitinib failure at our institutes. Results were …
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