[HTML][HTML] Therapeutic efficacy of gefitinib and erlotinib in patients with advanced lung adenosquamous carcinoma

Z Song, B Lin, L Shao, Y Zhang - Journal of the Chinese Medical …, 2013 - Elsevier
Adenosquamous carcinoma (ASC) of the lung is a rare subtype of nonsmall-cell lung cancer
(NSCLC). To date, the efficacious targeted therapy for advanced ASC remains unclear and …

Response to Erlotinib in Patients with EGFR Mutant Advanced Non–Small Cell Lung Cancers with a Squamous or Squamous-like Component

PK Paik, AM Varghese, CS Sima, AL Moreira… - Molecular cancer …, 2012 - AACR
… cell carcinomas (SCC) of the lung, these mutations do occur in adenosquamous carcinomas
(… Here we present an expanded series of these cases with a focus on sensitivity to erlotinib. …

Retrospective study of erlotinib in patients with advanced squamous lung cancer

JS Tseng, TY Yang, KC Chen, KH Hsu, HY Chen… - Lung Cancer, 2012 - Elsevier
lung SCC. The aim of this study was to evaluate the status of erlotinib treatment and EGFR
mutation in lung SCC patients. … types of lung cancer include adenocarcinoma, squamous cell …

A phase 2 trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus

DH Ilson, D Kelsen, M Shah, G Schwartz, DA Levine… - Cancer, 2011 - Wiley Online Library
erlotinib, reportedly have antitumor activity in patients with nonsmall cell lung cancer and
head and neck cancer … of the EGFR TKI erlotinib in patients with esophageal cancer who had …

Adenosquamous carcinoma of the lung

C Li, H Lu - OncoTargets and therapy, 2018 - Taylor & Francis
… squamous cell carcinoma (SCC). Although ASC has biological … stage III patients with ASC.
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) such as erlotinib and …

Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib

YY Janjigian, CG Azzoli, LM Krug, LK Pereira… - Clinical cancer …, 2011 - AACR
… resistance to erlotinib in patients with lung adenocarcinoma. To … and erlotinib in patients
with acquired resistance to erlotinib, … Experimental Design: Patients with lung adenocarcinoma

Combining Erlotinib and Cetuximab Is Associated with Activity in Patients with Non–Small Cell Lung Cancer (Including Squamous Cell Carcinomas) and Wild-Type …

JJ Wheler, AM Tsimberidou, GS Falchook… - Molecular cancer …, 2013 - AACR
… In summary, erlotinib and cetuximab treatment was … months/PR in five of 20 patients with
non–small cell lung cancer (25%), … 6 patients with adenocarcinoma histology versus 4 patients

Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled …

JC Soria, E Felip, M Cobo, S Lu, K Syrigos… - The lancet …, 2015 - thelancet.com
… of adenocarcinoma are contraindicated in patients with squamous cell … for patients with
squamous cell carcinoma of the lung. Afatinib reduced the risk of death compared with erlotinib

Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - … Lancet Respiratory …, 2018 - thelancet.com
… 19, and patients with adenocarcinoma (figure … erlotinib and chemotherapy in patients
who were smokers, those with EGFR mutation type exon 21, and patients with non-adenocarcinoma

… mutations with clinical outcomes of afatinib-or erlotinib-treated patients with lung squamous cell carcinoma: secondary analysis of the LUX-Lung 8 randomized clinical …

GD Goss, E Felip, M Cobo, S Lu, K Syrigos… - JAMA …, 2018 - jamanetwork.com
… in heavily pretreated patients with adenocarcinoma NSCLC whose tumors had such a …
study was different from that observed in adenocarcinoma NSCLC, in which the most frequently …