[HTML][HTML] Erlotinib in lung cancer—molecular and clinical predictors of outcome

MS Tsao, A Sakurada, JC Cutz, CQ Zhu… - … England Journal of …, 2005 - Mass Medical Soc
… benefit from erlotinib. To clarify the role of EGFR in the outcome of non–small-cell lung cancer,
we … of EGFR, and mutation status of the gene in a subgroup of patients in the BR.21 study. …

[HTML][HTML] Erlotinib in previously treated non–small-cell lung cancer

FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
… to determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs
survival in non–small-cell lung cancer after the failure of first-line or second-line chemotherapy. …

Erlotinib: a new therapeutic approach for non-small cell lung cancer

P Bonomi - Expert opinion on investigational drugs, 2003 - Taylor & Francis
patients with EGFR-negative tumours. In contrast, increasing severity of rash in erlotinib-treated
lung cancer patients was … cancer and head and neck cancer patients [44]. The median …

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… Symptom improvement in lung cancer patients treated with erlotinib: quality of life
analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. …

Retrospective study of erlotinib in patients with advanced squamous lung cancer

JS Tseng, TY Yang, KC Chen, KH Hsu, HY Chen… - Lung Cancer, 2012 - Elsevier
… low in lung SCC. The aim of this study was to evaluate the status … erlotinib treatment and
EGFR mutation in lung SCC patients. Methods: We retrospectively enrolled lung cancer patients

Erlotinib in patients with advanced lung squamous cell carcinoma

CL Chiang, CM Tsai, TY Chou, YM Chen… - Cancer chemotherapy …, 2013 - Springer
patients with advanced LSQC treated with erlotinib monotherapy during January 2006 to
October 2011. We included lung cancer patients … , had history of erlotinib treatment, and had …

Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer

JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
… Our objective was to assess the pharmacokinetics of erlotinib in a large patient population
with … and diarrhea) in patients with non-small cell lung cancer receiving single-agent erlotinib. …

Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial

YL Wu, JS Lee, S Thongprasert, CJ Yu, L Zhang… - The lancet …, 2013 - thelancet.com
… or placebo with gemcitabine and carboplatin or cisplatin followed by maintained erlotinib
or placebo in patients with stage IIIB/IV non-small-cell lung cancer. The study was undertaken …

Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer

Y Togashi, K Masago, S Masuda, T Mizuno… - Cancer chemotherapy …, 2012 - Springer
Purpose Several cases have been reported in which central nervous system (CNS) metastases
of non-small cell lung cancer (NSCLC) resistant to gefitinib were improved by erlotinib. …

Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non–small-cell lung cancer: a phase III trial

GV Scagliotti, M Krzakowski, A Szczesna… - Journal of clinical …, 2012 - ascopubs.org
erlotinib may enhance antitumor activity compared with either agent alone in non–small-cell
lung cancer (… plus erlotinib versus placebo plus erlotinib in patients with refractory NSCLC. …