Comparison of gefitinib versus erlotinib in patients with nonsmall cell lung cancer who failed previous chemotherapy

ST Kim, J Lee, J Kim, YW Won, JM Sun, J Yun… - Cancer, 2010 - Wiley Online Library
… that gefitinib and erlotinib appeared to have similar outcomes in patients with advanced/…
chemotherapy. The overall response rates and disease control rates in the gefitinib- and erlotinib

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
… to be the sequela of previous platinum-based chemotherapy. … II trial of erlotinib or standard
chemotherapy in patients with … for patients who developed moderate to severe skin rash on …

High efficacy of erlotinib in Taiwanese NSCLC patients in an expanded access program study previously treated with chemotherapy

RP Perng, CH Yang, YM Chen, GC Chang, MC Lin… - Lung Cancer, 2008 - Elsevier
… (EGFR) pathway with tyrosine kinase inhibitor (TKI) is an effective and promising salvage
treatment for NSCLC patients who have failed previous chemotherapy, especially for Asian …

Chemotherapy with erlotinib or chemotherapy alone in advanced non‐small cell lung cancer with acquired resistance to EGFR tyrosine kinase inhibitors

SB Goldberg, GR Oxnard, S Digumarthy… - The …, 2013 - academic.oup.com
chemotherapy alone after the development of TKI resistance. We found that continuing
erlotinib with chemotherapy … a reasonable treatment option for patients with EGFR‐mutant lung …

A phase II pharmacodynamic study of erlotinib in patients with advanced non–small cell lung cancer previously treated with platinum-based chemotherapy

E Felip, F Rojo, M Reck, A Heller, B Klughammer… - Clinical Cancer …, 2008 - AACR
… In summary, the findings of this study concur with those of previous research and suggest …
for clinical benefit with erlotinib in patients with NSCLC. Erlotinib suppressed EGFR-mediated …

[HTML][HTML] Erlotinib in previously treated non–small-cell lung cancer

FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
… The patients had to have received one or two regimens of combination chemotherapy and
not be eligible for further chemotherapy. Patients 70 years of age or older may have received …

Chemotherapy plus erlotinib versus chemotherapy alone for treating advanced non-small cell lung cancer: a meta-analysis

JL Xu, B Jin, ZH Ren, YQ Lou, ZR Zhou, QZ Yang… - PloS one, 2015 - journals.plos.org
… In this meta-analysis, continuous erlotinib plus chemotherapy versus chemotherapy alone
failed to show improvements in PFS and OS. A previous systematic review demonstrated that …

Clinical efficacy of erlotinib in patients previously treated for advanced non‐small cell lung cancer

S Zhou, S Ren, L Yan, L Zhang, L Tang, J Zhang… - …, 2009 - Wiley Online Library
patients received erlotinib at a fixed oral dose of 150 mg daily and concomitant use of
chemotherapeutic … stage, previous treatments and smoking status was performed on the 108 …

Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non–small-cell lung cancer

TSK Mok, YL Wu, CJ Yu, C Zhou, YM Chen… - Journal of Clinical …, 2009 - ascopubs.org
… combination of chemotherapy with erlotinib, followed by erlotinib maintenance therapy. …
administration of erlotinib with chemotherapy has demonstrated promising results in patients with …

Approval summary for erlotinib for treatment of patients with locally advanced or metastatic non–small cell lung cancer after failure of at least one prior chemotherapy …

JR Johnson, M Cohen, R Sridhara, YF Chen… - Clinical Cancer …, 2005 - AACR
… EGFR status measured by immunohistochemistry was not a predictor of tumor response in
previous lung cancer clinical trials with erlotinib or gefitinib, a related EGFR tyrosine kinase …