Comparison of gefitinib versus erlotinib in patients with nonsmall cell lung cancer who failed previous chemotherapy
… that gefitinib and erlotinib appeared to have similar outcomes in patients with advanced/…
chemotherapy. The overall response rates and disease control rates in the gefitinib- and erlotinib…
chemotherapy. The overall response rates and disease control rates in the gefitinib- and erlotinib…
Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
… to be the sequela of previous platinum-based chemotherapy. … II trial of erlotinib or standard
chemotherapy in patients with … for patients who developed moderate to severe skin rash on …
chemotherapy in patients with … for patients who developed moderate to severe skin rash on …
[HTML][HTML] A randomized phase II study comparing erlotinib versus erlotinib with alternating chemotherapy in relapsed non-small-cell lung cancer patients: the NVALT-10 …
JG Aerts, H Codrington, NAG Lankheet, S Burgers… - Annals of oncology, 2013 - Elsevier
… Therefore, we designed a study in patients who failed previous cytotoxic treatment to
compare PFS between erlotinib and intercalating erlotinib with pemetrexed for NSQ cell lung …
compare PFS between erlotinib and intercalating erlotinib with pemetrexed for NSQ cell lung …
High efficacy of erlotinib in Taiwanese NSCLC patients in an expanded access program study previously treated with chemotherapy
RP Perng, CH Yang, YM Chen, GC Chang, MC Lin… - Lung Cancer, 2008 - Elsevier
… (EGFR) pathway with tyrosine kinase inhibitor (TKI) is an effective and promising salvage
treatment for NSCLC patients who have failed previous chemotherapy, especially for Asian …
treatment for NSCLC patients who have failed previous chemotherapy, especially for Asian …
Approval summary for erlotinib for treatment of patients with locally advanced or metastatic non–small cell lung cancer after failure of at least one prior chemotherapy …
JR Johnson, M Cohen, R Sridhara, YF Chen… - Clinical Cancer …, 2005 - AACR
… EGFR status measured by immunohistochemistry was not a predictor of tumor response in
previous lung cancer clinical trials with erlotinib or gefitinib, a related EGFR tyrosine kinase …
previous lung cancer clinical trials with erlotinib or gefitinib, a related EGFR tyrosine kinase …
First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
SM Lee, I Khan, S Upadhyay, C Lewanski… - The lancet …, 2012 - thelancet.com
… assigned 350 patients to receive erlotinib and 320 to receive placebo. We followed up patients
until … Exclusion criteria were previous treatment with any biological anticancer therapy; …
until … Exclusion criteria were previous treatment with any biological anticancer therapy; …
Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non–small-cell lung cancer
… combination of chemotherapy with erlotinib, followed by erlotinib maintenance therapy. …
administration of erlotinib with chemotherapy has demonstrated promising results in patients with …
administration of erlotinib with chemotherapy has demonstrated promising results in patients with …
Chemotherapy with erlotinib or chemotherapy alone in advanced non‐small cell lung cancer with acquired resistance to EGFR tyrosine kinase inhibitors
SB Goldberg, GR Oxnard, S Digumarthy… - The …, 2013 - academic.oup.com
… chemotherapy alone after the development of TKI resistance. We found that continuing
erlotinib with chemotherapy … a reasonable treatment option for patients with EGFR‐mutant lung …
erlotinib with chemotherapy … a reasonable treatment option for patients with EGFR‐mutant lung …
Chemotherapy plus erlotinib versus chemotherapy alone for treating advanced non-small cell lung cancer: a meta-analysis
JL Xu, B Jin, ZH Ren, YQ Lou, ZR Zhou, QZ Yang… - PloS one, 2015 - journals.plos.org
… In this meta-analysis, continuous erlotinib plus chemotherapy versus chemotherapy alone
failed to show improvements in PFS and OS. A previous systematic review demonstrated that …
failed to show improvements in PFS and OS. A previous systematic review demonstrated that …
Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a …
T Ciuleanu, L Stelmakh, S Cicenas, S Miliauskas… - The lancet …, 2012 - thelancet.com
… The main exclusion criteria were previous exposure to anti-human-EGFR-directed drugs
or … and dihydrofolate reductase inhibitors); previous chemotherapy or systemic anti-neoplastic …
or … and dihydrofolate reductase inhibitors); previous chemotherapy or systemic anti-neoplastic …
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