[HTML][HTML] Erlotinib-related skin toxicities: treatment strategies in patients with metastatic non-small cell lung cancer

Y Kiyohara, N Yamazaki, A Kishi - Journal of the American Academy of …, 2013 - Elsevier
… therapy, thereby enabling patients to achieve optimal benefits. … the most common
erlotinib-related skin disorders in patients with … skin disorders reported with erlotinib are acneiform …

Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: results of an Experts Panel Meeting

C Gridelli, P Maione, D Amoroso, M Baldari… - Critical reviews in …, 2008 - Elsevier
erlotinib-related skin rash, data from 485 patients enrolled onto the phase III randomized trial
(BR.21) of erlotinib … NSCLC show that skin rash occurred in 75% of the patient population [7]…

Erlotinib-induced skin rash in patients with non–small-cell lung cancer: pathogenesis, clinical significance, and management

S Tsimboukis, I Merikas, EM Karapanagiotou… - Clinical lung cancer, 2009 - Elsevier
… of rash and response and/or survival, making rash a … of erlotinib-induced skin rash and
establishes a treatment strategy to help treat dermatologic adverse events and allow patients to …

[PDF][PDF] Skin rash as useful marker of erlotinib efficacy in NSCLC and its impact on clinical practice

O Fiala, M Pesek, J Fínek, J Krejci, J Ricar… - Neoplasma, 2013 - researchgate.net
Rash is associated with a good therapeutic response. We aimed at the evaluation of rash
as a predictor of therapeutic effect of erlotinib in patients … Totally 184 patients with advanced …

[HTML][HTML] Dosing to rash: a phase II trial of the first-line erlotinib for patients with advanced non-small-cell lung cancer an Eastern Cooperative Oncology Group Study …

JR Brahmer, JW Lee, AM Traynor, MM Hidalgo… - European Journal of …, 2014 - Elsevier
… that by increasing the dose of erlotinib until the development of a grade 2 or tolerable skin
rash, response and survival would be improved. This study of erlotinib in the first-line setting of …

[PDF][PDF] Erlotinib-induced skin rash. Pathogenesis, clinical significance and management in pancreatic cancer patients

MW Saif, I Merikas, S Tsimboukis, K Syrigos - Jop, 2008 - Citeseer
… side effect in patients receiving erlotinib is skin rash, as discussed … Skin rash often hampers
significantly the quality of life and … the pathogenesis of the erlotinib induced skin rash and we …

[HTML][HTML] Dosing to rash?–The role of erlotinib metabolic ratio from patient serum in the search of predictive biomarkers for EGFR inhibitor-mediated skin rash

M Steffens, T Paul, V Hichert, C Scholl… - European Journal of …, 2016 - Elsevier
… predictive effect of the erlotinib/O-desmethyl-erlotinib ratio to skin rash in terms of PFS and …
of erlotinib/O-desmethyl-erlotinib ratio as biomarker in comparison to skin rash might be that it …

Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
… EGFR mutation-negative patients who presented with a skin rash … of erlotinib depending
on the presence of a rash, we suggest that erlotinib may be more effective in patients with a rash

Influence of skin color in the development of erlotinib-induced rash: a report from the SERIES clinic

SE Lai, L Minnelly, P O'Keeffe, A Rademaker… - Journal of Clinical …, 2007 - ascopubs.org
… of skin pigmentation would be associated with higher frequency and severity … erlotinib
rash. Methods: We conducted a retrospective chart review of 42 patients undergoing erlotinib

Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer

S Kanazawa, K Yamaguchi, Y Kinoshita, K Siomi… - Platelets, 2009 - Taylor & Francis
… Here, we describe two NSCLC patients who received erlotinib therapy and developed a skin
rash, … Our results suggest that the mechanism of the skin rash development after erlotinib