Phase II study of erlotinib in advanced non–small-cell lung cancer after failure of gefitinib

BC Cho, CK Im, MS Park, SK Kim, J Chang… - Journal of clinical …, 2007 - ascopubs.org
… predicts the response to gefitinib or erlotinib in several studies. However, a lack of correlation
between EGFR mutations and response to erlotinib was observed in this study. A potential …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… all patients according to different lines of gefitinib or erlotinib. The disparities of choices on
gefitinib or erlotinib (more male, non-adenocarcinoma and smokers using erlotinib) were still …

Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study

IF Emery, C Battelli, PL Auclair, K Carrier, DM Hayes - BMC cancer, 2009 - Springer
… our lung cancer patients to compare the benefits derived from erlotinib and gefitinib and to
… We subsequently analyzed tumor tissue from a subgroup of these patients for a pilot study to …

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
… , this study demonstrated that both gefitinib and erlotinibstudy with inclusion of both
gefitinib and erlotinib in a properly conducted and powered phase III trial in an enriched patient

A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
… Finally, the efficacy data for erlotinib and gefitinibstudy. In conclusion, the primary end
point was not met in the present study, and erlotinib was not significantly superior to gefitinib in …

Randomized phase III study comparing gefitinib with erlotinib in patients with previously treated advanced lung adenocarcinoma: WJOG 5108L

Y Urata, N Katakami, S Morita, R Kaji… - Journal of Clinical …, 2016 - ascopubs.org
… with lung adenocarcinoma were randomly assigned to receive gefitinib or erlotinib. This
study aimed to investigate the noninferiority of gefitinib compared with erlotinib. The primary end …

[HTML][HTML] Gefitinib or erlotinib in the treatment of advanced non-small cell lung cancer

YY Shao, CC Lin, CH Yang - Discovery Medicine, 2010 - discoverymedicine.com
… Many phase II or III studies have proven the efficacy of gefitinib or erlotinib as the first-line, …
not clear whether gefitinib or erlotinib has different activities in advanced NSCLC patients with …

Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer

Y Togashi, K Masago, S Masuda, T Mizuno… - Cancer chemotherapy …, 2012 - Springer
… concentrations of gefitinib and erlotinib have never been directly compared. Thus, in the …
study, we investigated the plasma and CSF concentrations of gefitinib and erlotinib in patients

[HTML][HTML] Phase II study of erlotinib as a salvage treatment for non-small-cell lung cancer patients after failure of gefitinib treatment

DH Lee, SW Kim, C Suh, DH Yoon, EJ Yi, JS Lee - Annals of oncology, 2008 - Elsevier
… We conducted a phase II study of erlotinib after failure of gefitinib treatment in patients with
… In our study, of the 15 patients who benefited from gefitinib, two benefited from erlotinib

Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer: a retrospective analysis

T Yoshida, K Yamada, K Azuma, A Kawahara, H Abe… - Medical oncology, 2013 - Springer
… All patients in this study were included in the analysis of AEs. Comparisons of AEs between
the gefitinib and erlotinib groups are summarized in Table 2. Major AEs seen in both groups …