Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer
EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
… explored, but no current phase III data show superiority of an … An association between
estrogens and lung cancer risk first … when an increase in lung cancer mortality was observed in …
estrogens and lung cancer risk first … when an increase in lung cancer mortality was observed in …
Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non–small-cell lung cancer
TG Karrison, ML Maitland, WM Stadler… - … of the National Cancer …, 2007 - academic.oup.com
… -molecule tyrosine kinase inhibitor erlotinib may be considered … consisting of the oral agents
erlotinib and sorafenib, an … activity than erlotinib alone to merit a subsequent phase III trial. …
erlotinib and sorafenib, an … activity than erlotinib alone to merit a subsequent phase III trial. …
Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials
M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… or gefitinib as treatment of advanced or metastatic stage IIIB … Cancer classification. The
following study selection criteria were used: phase II and phase III randomized studies of erlotinib …
following study selection criteria were used: phase II and phase III randomized studies of erlotinib …
[HTML][HTML] Maintenance erlotinib versus erlotinib at disease progression in patients with advanced non-small-cell lung cancer who have not progressed following …
S Cicènas, SL Geater, P Petrov, Y Hotko, G Hooper… - Lung Cancer, 2016 - Elsevier
… IUNO was a randomized, double-blind, multicenter, placebo-controlled phase III trial of
maintenance erlotinib versus erlotinib at the time of disease progression in patients with …
maintenance erlotinib versus erlotinib at the time of disease progression in patients with …
Experience with erlotinib in the treatment of non-small cell lung cancer
L Landi, F Cappuzzo - Therapeutic Advances in Respiratory …, 2015 - journals.sagepub.com
… The ATLAS trial was a phase III study comparing maintenance erlotinib plus bevacizumab
versus bevacizumab alone in patients with NSCLC without progressive disease after four …
versus bevacizumab alone in patients with NSCLC without progressive disease after four …
… Phase III Study of First-Line Erlotinib Followed by Second-Line Cisplatin/Gemcitabine Versus First-Line Cisplatin/Gemcitabine Followed by Second-Line Erlotinib in …
C Gridelli, C Butts, F Ciardiello, R Feld, C Gallo… - Clinical lung cancer, 2008 - Elsevier
… Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small
cell lung cancer: the Tarceva Lung Cancer … TRIBUTE: a phase III trial of erlotinib …
cell lung cancer: the Tarceva Lung Cancer … TRIBUTE: a phase III trial of erlotinib …
[HTML][HTML] … the randomized, placebo-controlled, phase 3, FASTACT-2 study of intercalated erlotinib with first-line chemotherapy in advanced non-small-cell lung cancer …
TSK Mok, JS Lee, L Zhang, C Yu, S Thongprasert… - Annals of …, 2012 - Elsevier
… FASTACT-2 is a randomized, placebo-controlled, phase 3 study in first-line advanced
NSCLC, which met its primary endpoint of significantly prolonged PFS with intercalated erlotinib …
NSCLC, which met its primary endpoint of significantly prolonged PFS with intercalated erlotinib …
[HTML][HTML] Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line …
… In the placebo-controlled phase III SATURN study, maintenance erlotinib after first-line
chemotherapy demonstrated significantly prolonged progression-free survival (PFS) and overall …
chemotherapy demonstrated significantly prolonged progression-free survival (PFS) and overall …
Erlotinib in cancer treatment
MA Bareschino, C Schettino, T Troiani, E Martinelli… - Annals of oncology, 2007 - Elsevier
… in three common lung cancer symptoms, showed that patients receiving … Phase III
randomized trials with erlotinib in advanced non-small cell lung cancer and pancreatic cancer …
randomized trials with erlotinib in advanced non-small cell lung cancer and pancreatic cancer …
Results of a phase III trial of erlotinib (OSI-774) combined with cisplatin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer (NSCLC)
U Gatzemeier, A Pluzanska, A Szczesna… - Journal of Clinical …, 2004 - ascopubs.org
… -naive patients with unresectable stage III or IV NSCLC; age … erlotinib combined with GC
was not significantly inferior to GC alone, with the exception of increased incidences of grade 3…
was not significantly inferior to GC alone, with the exception of increased incidences of grade 3…