Delineation of cell death mechanisms induced by synergistic effects of statins and erlotinib in non-small cell lung cancer cell (NSCLC) lines

A Otahal, D Aydemir, E Tomasich, C Minichsdorfer - Scientific Reports, 2020 - nature.com
… resulted in synergistically enhanced cytotoxicity compared to pitavastatin monotherapy. …
All cell lines studied in this work were erlotinib resistant and EGFR wild type (Table 1). Cells

Erlotinib resistance in lung cancer: current progress and future perspectives

J Tang, R Salama, SM Gadgeel, FH Sarkar… - Frontiers in …, 2013 - frontiersin.org
Erlotinib, the epidermal growth factor receptor (EGFR)-targeting tyrosine … cell lung cancer
where it seems to be more effective in patients with EGFR mutations. Resistance to erlotinib is a …

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials

M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… following study subpopulations: nonselected monotherapy first line, maintenance or
consolidation with either gefitinib or erlotinib in first line, monotherapy second line, mutation positive …

Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non–small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial

U Gatzemeier, A Pluzanska, A Szczesna… - Journal of Clinical …, 2007 - ascopubs.org
… in survival in pancreatic cancer by adding a second … of erlotinib for the treatment of pancreatic
cancer in the United States. Furthermore, in a phase III trial (BR.21), erlotinib monotherapy

Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer

E Boutsikou, T Kontakiotis, P Zarogoulidis… - OncoTargets and …, 2013 - Taylor & Francis
… -carboplatin plus erlotinib administered orally at 150 mg/dL per day beginning on the first
day of the third cycle and continued with erlotinib monotherapy thereafter until progression. …

Efficacy and safety of erlotinib combined with bevacizumab in the treatment of non-small cell lung cancer: A systematic review and meta-analysis

K Zhou, S Zhao, W Guo, L Ding - Medicine, 2020 - journals.lww.com
… Our meta-analysis indicates that compared with monotherapy, erlotinib+bevacizumab
combination therapy prolongs PFS of patients with NSCLC, but cannot extend OS or elevate ORR. …

Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: a mono-institutional experience

CC Chang, KH Chi, SJ Kao, PS Hsu, YW Tsang… - Lung Cancer, 2011 - Elsevier
… (TKI) has proved effective for selective advanced lung cancer patients in Taiwan. We …
stage IIIb or IV non-squamous cell, non-small cell lung cancer (NSqCLC) who responded to …

… for the combination of erlotinib plus ramucirumab compared with osimertinib in previously untreated advanced or recurrent non–small cell lung cancer positive for the …

N Haratake, H Hayashi, M Shimokawa, Y Nakano… - Clinical lung cancer, 2022 - Elsevier
erlotinib and an angiogenesis inhibitor significantly prolonged PFS compared with erlotinib
monotherapy in … The RELAY study found that the combination of erlotinib and ramucirumab, a …

Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
… efficacy and safety of erlotinib for non-small cell lung cancer (NSCLC), … erlotinib at 14 sites
(17 departments) in Ibaraki (Japan) between December 2007 and December 2010. The tumor

Afatinib and Erlotinib in the treatment of squamous-cell lung cancer

M Tagliamento, C Genova, E Rijavec… - Expert Opinion on …, 2018 - Taylor & Francis
… The TRUST study was an open-label, phase IV study with erlotinib monotherapy in
patients with advanced NSCLC who had previously progressed after at least one previous …