The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor

BO Fabriek, MMJ Polfliet, RPM Vloet… - Blood, The Journal …, 2007 - ashpublications.org
… evidence that the surface receptor CD163 can function as an adhesion receptor for erythroblasts.
CD163 is highly expressed on macrophages in erythroblastic islands both in the bone …

The erythroblastic island

D Manwani, JJ Bieker - Current topics in developmental biology, 2008 - Elsevier
Adhesive interactions occur between α4β1 integrin expressed on erythroblasts and its
counter–receptor—vascular adhesion … Monoclonal antibodies to either receptor disrupt island …

Erythroblastic islands: niches for erythropoiesis

JA Chasis, N Mohandas - Blood, The Journal of the American …, 2008 - ashpublications.org
… proteins have been identified as receptors for erythroblasts, although their counterreceptors
… Such an effect occurring within erythroid niches would perturb matrix-erythroblast adhesive

Importance of cell-cell interactions in regulation of erythropoiesis

M Hanspal - Current opinion in hematology, 1997 - journals.lww.com
… The formation of erythroblastic islands involves adhesive inter… adhesion receptors in the
matu ration of erythroid cells. E-cadh e rin was shown to be expressed in human erythroblasts

Expression of a divalent cation-dependent erythroblast adhesion receptor by stromal macrophages from murine bone marrow

L Morris, PR Crocker, I Fraser, M Hill… - Journal of Cell …, 1991 - journals.biologists.com
… this receptor. … adhesion receptor on macrophages in adult as well as foetal tissues, that
macrophages express distinct, independently regulated haemopoietic cell interaction receptors

Very late activation antigen 4-vascular cell adhesion molecule 1 interaction is involved in the formation of erythroblastic islands.

Y Sadahira, T Yoshino, Y Monobe - The Journal of experimental …, 1995 - rupress.org
… cell adhesion molecule 1 (VCAM-1). The surrounding erythroblasts of the erythroblastic
4 (VLA-4:a4B1 integrin), the counter receptor of VCAM-1, whereas most reticulocytes and …

Novel cell surface adhesion receptors involved in interactions between stromal macrophages and haematopoietic cells

PR Crocker, L Morris, S Gordon - Journal of Cell Science, 1988 - journals.biologists.com
… -dependent adhesion system. Using erythroblasts as a ligand, FLM were selected to
explore the properties and expression of this adhesion receptor, the erythroblast receptor (EbR). …

Modulation of erythroid adhesion receptor expression by hydroxyurea in children with sickle cell disease

MH Odièvre, V Bony, M Benkerrou… - …, 2008 - haematologica.org
… Background We investigated adhesion receptor levels on red blood cells, … Expression of
adhesion receptors was analyzed by flow … Alterations of levels of adhesion receptors could be …

Adherence to macrophages in erythroblastic islands enhances erythroblast proliferation and increases erythrocyte production by a different mechanism than …

MM Rhodes, P Kopsombut… - Blood, The Journal …, 2008 - ashpublications.org
… binds interstitial cell adhesion molecule 4 on erythroblasts, 16 (3) erythroblast-macrophage …
sialated glycoproteins on erythroblasts, 18 and (5) CD163, the receptor for hemoglobin-…

Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation

G Lee, A Lo, SA Short, TJ Mankelow, F Spring… - Blood, 2006 - ashpublications.org
… We postulate that the novel receptor-counterreceptor interaction between erythroblast
ICAM-… be important not only for adhesive integrity of erythroblastic island structures but also for …