Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli

DR Hyduke, LR Jarboe, LM Tran… - Proceedings of the …, 2007 - National Acad Sciences
… transcription network structure. To attain this goal we used network component analysis (NCA…
that reflects the underlying biological structure of regulatory networks (25–27). NCA is able …

Construction and Analysis of Gene Co-Expression Networks in Escherichia coli

W Liu, L Li, X Long, W You, Y Zhong, M Wang, H Tao… - Cells, 2018 - mdpi.com
… The aims of our analysis were as follows: (1) to integrate the independent datasets, which
will help to overcome the limitations caused by sample size and statistical method bias; (2) to …

An integrated network approach identifies the isobutanol response network of Escherichia coli

MP Brynildsen, JC Liao - Molecular systems biology, 2009 - embopress.org
… and transcription network connectivity data, genetic knockouts, and network component
analysis (NCA) to map the initial isobutanol response network of Escherichia coli under aerobic …

[HTML][HTML] Exploring the multi-drug resistance in Escherichia coli O157: H7 by gene interaction network: a systems biology approach

SK Miryala, S Ramaiah - Genomics, 2019 - Elsevier
… A systematic workflow of AMR gene interaction network analysis of E. coli O157:H7 strain.
The list … The interactions are integrated with the sources like genomic context, high throughput …

Construction and analysis of an integrated biological network of Escherichia coli

Z Mao, T Huang, Q Yuan, H Ma - Systems Microbiology and …, 2022 - Springer
… To search key nodes in the integrated network, we analyzed the degree distribution of each
node of the integrated network. We also developed a new algorithm based on the full path …

Extensive cross-talk and global regulators identified from an analysis of the integrated transcriptional and signaling network in Escherichia coli

L Antiqueira, SC Janga, L da Fontoura Costa - Molecular BioSystems, 2012 - pubs.rsc.org
… activity of TFs in Escherichia coli. To study this integrated network we computed a set of
network measurements followed by principal component analysis (PCA), investigated the …

A system-wide network reconstruction of gene regulation and metabolism in Escherichia coli

A Grimbs, DF Klosik, S Bornholdt… - PLoS computational …, 2019 - journals.plos.org
… provide a network representation of the integrated gene regulatory and metabolic system for
… : We present an integrated network representation of gene regulation and metabolism of E. …

A Network Biology Approach to Decipher Stress Response in Bacteria Using Escherichia coli As a Model

SD Nagar, B Aggarwal, S Joon… - Omics: a journal of …, 2016 - liebertpub.com
… In this work, Escherichia coli was used to model the bacterial stress response. A Protein-Protein
Interaction Network was generated by integrating differentially expressed genes in eight …

Modular analysis of the transcriptional regulatory network of E. coli

O Resendis-Antonio, JA Freyre-Gonzalez… - TRENDS in …, 2005 - cell.com
network of Escherichia coli is currently the best-understood regulatory network of a single …
Motivated by statistical evidence, suggesting a hierarchical modular architecture in this network

An integrative, multi‐scale, genome‐wide model reveals the phenotypic landscape of Escherichia coli

J Carrera, R Estrela, J Luo, N Rai… - Molecular systems …, 2014 - embopress.org
… We focused on a genome‐scale model for Escherichia coli, a gram‐negative, facultative …
transduction network (EcoST) and its integration to the transcriptional and metabolic network