Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

E Ben-Menachem, AA Gabbai, A Hufnagel, J Maia… - Epilepsy research, 2010 - Elsevier
… Treatment with once-daily eslicarbazepine acetate 800 mg and 1200 mg was more effective
than placebo and generally well tolerated in patients with partial-onset seizures refractory to …

Eslicarbazepine acetate

PL McCormack, DM Robinson - CNS drugs, 2009 - Springer
… • Across the phase III trials,[22,24,25] the relative reductions from baseline in seizure
frequency with eslicarbazepine acetate 800 or 1200 mg once daily ranged from 33% to 45% …

Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
… in 2009 for adjunctive treatment in adult subjects of partial-onset seizures, with or without …
recent studies on eslicarbazepine acetate in the treatment of drug-resistant partial epilepsy. …

Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: results of a 1-year …

A Hufnagel, E Ben-Menachem, AA Gabbai, A Falcão… - Epilepsy Research, 2013 - Elsevier
OBJECTIVE: To evaluate the long-term safety, tolerability and efficacy of once-daily eslicarbazepine
acetate (ESL) as adjunctive therapy in adults with partial-onset seizures. METHODS…

Eslicarbazepine acetate (BIA 2-093)

L Almeida, P Soares-da-Silva - Neurotherapeutics, 2007 - Springer
… onset seizures and was found to be efficacious and well tolerated. Monotherapy studies in
adult epileptic patients and add-on studies in epileptic … III studies in adult epileptic patients are …

Long‐term efficacy and safety of eslicarbazepine acetate: results of a 1‐year open‐label extension study in partial‐onset seizures in adults with epilepsy

P Halász, JA Cramer, D Hodoba, A Członkowska… - …, 2010 - Wiley Online Library
… Purpose: To evaluate the long-term efficacy and safety of once daily eslicarbazepine
acetate (ESL) as adjunctive therapy for partial-onset seizures in adults with epilepsy. …

Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures

E Perucca, C Elger, P Halasz, A Falcao, L Almeida… - Epilepsy research, 2011 - Elsevier
… To evaluate the pharmacokinetics of eslicarbazepine acetate (ESL) at steady-state in
adults with partial-onset seizures who have taken ESL for at least 1 year with one or two …

Eslicarbazepine acetate: a double‐blind, add‐on, placebo‐controlled exploratory trial in adult patients with partial‐onset seizures

C Elger, M Bialer, JA Cramer, J Maia, L Almeida… - …, 2007 - Wiley Online Library
… one of three groups: treatment with eslicarbazepine acetate once daily (QD, n … Eslicarbazepine
acetate was efficacious and well tolerated as an adjunctive therapy of refractory epileptic

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures: a randomized, double‐blind, placebo‐controlled …

C Elger, P Halász, J Maia, L Almeida… - …, 2009 - Wiley Online Library
Purpose: To study the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive
therapy for refractory partial seizures in adults with ≥4 partial‐onset seizures (simple or …

Pharmacokinetics, efficacy, and tolerability of eslicarbazepine acetate in children and adolescents with epilepsy

L Almeida, I Minciu, T Nunes… - The Journal of …, 2008 - Wiley Online Library
… of eslicarbazepine acetate (ESL), a new voltage-gated sodium channel blocker, in epileptic
children … Similar to adults, ESL was rapidly metabolized to eslicarbazepine. In all age groups, …