Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
eslicarbazepine acetate in the treatment of drug-resistant partial epilepsy. Efficacy and safety
Eslicarbazepine acetate is not recommended below 18 years, but a published phase II trial …

A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures

R Rocamora - Therapeutic advances in neurological …, 2015 - journals.sagepub.com
Eslicarbazepine acetate is a is a once-daily antiepileptic … The eslicarbazepine acetate
development program included an … have consistently shown that eslicarbazepine acetate (800 to …

Assessment of efficacy and safety of eslicarbazepine acetate for the treatment of trigeminal neuralgia

A Sanchez‐Larsen, D Sopelana… - … journal of pain, 2018 - Wiley Online Library
Eslicarbazepine acetate is a third-generation antiepileptic … the efficacy, tolerability and safety
of eslicarbazepine for TN. … hypothesis that eslicarbazepine acetate is an effective, safe and …

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures: a randomized, double‐blind, placebo‐controlled …

C Elger, P Halász, J Maia, L Almeida… - …, 2009 - Wiley Online Library
… This article reports on the efficacy and safety of one of the three pivotal studies with ESL as
… Note: p-values are based on comparison between eslicarbazepine acetate (ESL) groups and …

Long‐term efficacy and safety of eslicarbazepine acetate: results of a 1‐year open‐label extension study in partial‐onset seizures in adults with epilepsy

P Halász, JA Cramer, D Hodoba, A Członkowska… - …, 2010 - Wiley Online Library
Purpose: To evaluate the long‐term efficacy and safety of once daily eslicarbazepine acetate
(ESL) as adjunctive therapy for partial‐onset seizures in adults with epilepsy. Methods: One…

Eslicarbazepine acetate (BIA 2-093)

L Almeida, P Soares-da-Silva - Neurotherapeutics, 2007 - Springer
… A, Responder rate (ie, proportion of patients with at least 50% decrease in number of seizures)
and; B, proportion of seizure-free patients in a phase II study with eslicarbazepine acetate

Efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: integrated analysis of pooled data from double‐blind phase III …

A Gil‐Nagel, C Elger, E Ben‐Menachem, P Halász… - …, 2013 - Wiley Online Library
Purpose: To evaluate the efficacy and safety profile of eslicarbazepine acetate (ESL) added
to stable antiepileptic therapy in adults with partial‐onset seizures. Methods: Data from …

Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures

A Gil‐Nagel, J Lopes‐Lima, L Almeida… - Acta Neurologica …, 2009 - Wiley Online Library
… evaluate the efficacy and safety of eslicarbazepine acetate (… Eslicarbazepine acetate (ESL)
is a novel voltage-gated … is rapidly and extensively metabolized to eslicarbazepine (the entity …

Efficacy and safety of eslicarbazepine acetate versus controlled‐release carbamazepine monotherapy in newly diagnosed epilepsy: a phase III double‐blind …

E Trinka, E Ben‐Menachem, PA Kowacs, C Elger… - …, 2018 - Wiley Online Library
Objective We assessed the efficacy and safety of once‐daily eslicarbazepine acetate in
comparison with twice‐daily ( BID ) controlled‐release carbamazepine (carbamazepine‐ CR ) …

Pooled efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: Data from four double‐blind placebo‐controlled …

C Elger, M Koepp, E Trinka… - CNS Neuroscience …, 2017 - Wiley Online Library
… Pooled evaluation of the key efficacy and safety profile of eslicarbazepine acetate (ESL) …
Eslicarbazepine acetate is metabolized initially solely to eslicarbazepine and then subsequently …