… , particularly amplifications, in esophageal cancer, the ability to … of patients with both
esophageal adenocarcinoma and SCC … from past trials of esophageal cancer, highlight ongoing …

… carcinoma (ESCC) and esophageal adenocarcinoma (EAC), among which ESCC is the most
common histological type in the “Asian esophageal carcinoma … ) signaling pathway is one …

… Given that the combination of inhibitors targeted more than one molecule in a signaling
pathway, we examined the efficiency of the combination of MK2206/BEZ235 in esophageal …

… signaling pathway has anticancer effects in vitro and in vivo. Our results from esophageal
cancer cell lines and human esophageal … for esophageal carcinoma: a report of 495 patients …

… new recurrent genetic alterations and specific signaling pathways associated with EAC. The
… (PI3K) pathway was the most frequently altered oncogenic pathway by mutations and CNAs …

… Metastasis is the most lethal hallmark of esophageal squamous cell carcinoma (ESCC). The
aim of the study is to identify key signaling pathways that control metastasis in ESCC. Highly …

… in esophageal cancers that over-express cell cycle genes, PARP inhibitors for esophageal
… mutations, LGK974 for esophageal cancers with an activated Wnt signaling pathway, and a …

… To further verify the regulatory relationship between RUNX2 and the PI3K/AKT and ERK
signaling pathways in esophageal carcinoma, a PI3K/AKT pathway inhibitor LY294002 and an …

… cancers, and WNT/β-catenin pathway is also known to be involved in … signaling pathway in
esophageal carcinoma remains unknown. The expression of LKB1 in 62 cases of esophageal …

… signaling pathways. The genes could also be considered as potential candidate biomarkers
for therapeutic targets for this malignancy. Furthermore, our study would shed light on the …