Effect of genipin on cholestasis induced by estradiol‐17β‐glucuronide and lithocholate‐3‐O‐glucuornide in rats
H Goto, H Takikawa - Hepatology Research, 2010 - Wiley Online Library
… In the present study, we examined the effect of genipin on cholestasis induced by E17G
and LCG, Mrp2 substrates, in rats. Furthermore, the effect of genipin on the biliary excretion of …
and LCG, Mrp2 substrates, in rats. Furthermore, the effect of genipin on the biliary excretion of …
[PDF][PDF] Genipin enhances Mrp2 (Abcc2)‐mediated bile formation and organic anion transport in rat liver
J Shoda, T Miura, H Utsunomiya, K Oda… - …, 2004 - Wiley Online Library
… Considerable evidence29 suggests that genipin may exert its … genipin have not been clarified,
we hypothesize that genipin … genipininduced choleretic activity is mediated by its effect on …
we hypothesize that genipin … genipininduced choleretic activity is mediated by its effect on …
Potential role of genipin in cancer therapy
… of 17β-estradiol pellets. Tumor volume was significantly higher in MCF-7-UCP2 over-expressing
cells compared of MCF-7 parental cells [51]. In a urethane-induced lung carcinogenesis …
cells compared of MCF-7 parental cells [51]. In a urethane-induced lung carcinogenesis …
The protective effect of 17β-estradiol against hydrogen peroxide-induced apoptosis on mesenchymal stem cell
HY Chen, X Zhang, SF Chen, YX Zhang, YH Liu… - Biomedicine & …, 2012 - Elsevier
… But the protective effects of estrogen … effect of 17β-estradiol (17β-E2) against H 2 O 2 -induced
cell death in mice BMSCs and investigate the underlying antiapoptotic mechanism of 17β-…
cell death in mice BMSCs and investigate the underlying antiapoptotic mechanism of 17β-…
[HTML][HTML] Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin
V Ayyasamy, KM Owens, MM Desouki, P Liang… - PloS one, 2011 - journals.plos.org
… Genipin, a plant … Effect is mediated by UCP2; ii) UCP2 is over-expressed in breast and many
other cancers; iii) UCP2 promotes tumorigenic properties in vitro and in vivo and iv) genipin …
other cancers; iii) UCP2 promotes tumorigenic properties in vitro and in vivo and iv) genipin …
[HTML][HTML] Genipin, an inhibitor of UCP2 as a promising new anticancer agent: a review of the literature
YS Cho - International Journal of Molecular Sciences, 2022 - mdpi.com
… two days after subcutaneous implantation of 17β-estradiol pellets. Tumor size was significantly
greater in MCF-7-UCP2 over-expressing cells compared to MCF-7 parental cells [37]. …
greater in MCF-7-UCP2 over-expressing cells compared to MCF-7 parental cells [37]. …
Genipin attenuates mitochondrial-dependent apoptosis, endoplasmic reticulum stress, and inflammation via the PI3K/AKT pathway in acute lung injury
X Luo, B Lin, Y Gao, X Lei, X Wang, Y Li, T Li - International …, 2019 - Elsevier
… The protective effects of genipin against lipopolysaccharide (… Genipin performs its
pharmacological effects via activation of … in the protective effects of genipin against mitochondrial-…
pharmacological effects via activation of … in the protective effects of genipin against mitochondrial-…
Effect of penicillin G on the biliary excretion of cholephilic compounds in rats
M Fukami, A Tanka, H Takikawa - Journal of hepato-biliary-pancreatic …, 2011 - Springer
… The effect of penicillin G on the biliary excretion of … the effect of penicillin G on cholestasis
induced by estradiol-17β-… We previously reported that genipin inhibited biliary EM excretion …
induced by estradiol-17β-… We previously reported that genipin inhibited biliary EM excretion …
Geniposide in Gardenia jasminoides var. radicans Makino modulates blood pressure via inhibiting WNK pathway mediated by the estrogen receptors
Y Fu, P Yuan, Y Cao, Y Ke, Q Zhang… - Journal of Pharmacy …, 2020 - academic.oup.com
… significantly increases the protein expressions of estrogen receptor α (ERα), estrogen receptor
β (ERβ) … of NKCC and NCC and could be antagonistic to estrogen receptor antagonists. …
β (ERβ) … of NKCC and NCC and could be antagonistic to estrogen receptor antagonists. …
Expression and hormone regulation of UCP2 in goat uterus
Y Sun, LG Bu, B Wang, J Ren, TY Li, LL Kong… - Animal reproduction …, 2022 - Elsevier
… in goat EECs following progesterone (P 4 ) or 17β-estradiol (E 2 ) treatment (each n = 3). …
treated with genipin, the specific inhibitor of UCP2. Our in vitro findings were that genipin down-…
treated with genipin, the specific inhibitor of UCP2. Our in vitro findings were that genipin down-…
相关搜索
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