… , HCT116 and DLD-1 cells were responsive only to high (10 nM) estrogen concentrations,
and LoVo cells were responsive to 1 and 10 nM estrogen concentrations. This differential …

… in pathobiological role of estrogens in postmenopausal colon cancer according to the …
colon cancer to simplify such complicated situations associated with CRC and the estrogen …

… This may result in a cell context-specific concentration of these sex steroids, including
estrogens. This is particularly relevant since 17βHSD types 2 and 4, but not other iso-enzymes, …

… against the development of colon cancer. … colon cancer line Caco2 was reported to grow
at a very slow rate in the absence of estradiol and to respond to physiological concentrations …

… 17β-estradiol (E 2 ) was used at physiological concentrations … , and estrogen receptors in
colorectal cancer cells provides … for estrogen in the neoplastic progression of colon cancer. …

… We therefore tested high concentrations of estrogen (up to 500 nM) in the proliferation
assay, but no effect was observed. Further verification of the action of ERß on the growth of …

… Colon cancer incidence and mortality rates are lower in females compared with … that estrogen
replacement therapy (ERT) reduces cancer risk in postmenopausal women. Two estrogen …

… The concentration of estrogen, that is markedly different in the premenopausal versus
postmenopausal period when women do not use HRT, may determine if the direct or indirect effect …

… ” human colorectal cancer cells are able to metabolize estrogens in their … estrogen
concentration and, ultimately, to the cellular responsiveness to … Reproductive factors and colon …

… highest cause of death from cancer with 430,000 deaths globally per year. Estrogen has
also been implicated in the development and progression of colon cancer. Also sex-specific …