Estrogen receptor beta as target for colorectal cancer prevention
… Min/+ mice Both estrogen receptors inhibited tumorgenesis in proximal colon of Apc Min/+
mice in both genders, whereas small intestinal tumors were unaffected. Homozygous ERα …
mice in both genders, whereas small intestinal tumors were unaffected. Homozygous ERα …
Colorectal cancer risk associated with hormone use varies by expression of estrogen receptor-β
A Rudolph, C Toth, M Hoffmeister, W Roth, E Herpel… - Cancer research, 2013 - AACR
… in colorectal cancer, we assessed the risk of these malignancies according to tumor expression
of estrogen receptor-β (… in 445 cases of incident colorectal cancer. Unconditional logistic …
of estrogen receptor-β (… in 445 cases of incident colorectal cancer. Unconditional logistic …
Estrogen receptor β expression and colorectal cancer: a systematic review and meta-analysis
Y Niv - European journal of gastroenterology & hepatology, 2015 - journals.lww.com
… The incidence of colorectal cancer (CRC) is lower, and the prognosis is better in women till
… estrogen receptor β (ERβ) is abundant in the large bowel, may be activated by estrogen in …
… estrogen receptor β (ERβ) is abundant in the large bowel, may be activated by estrogen in …
[HTML][HTML] Association of estrogen receptor betavariants and serum levels of estradiol with risk of colorectal cancer: a case control study
H Wu, L Xu, J Chen, J Hu, S Yu, G Hu, L Huang… - BMC cancer, 2012 - Springer
… of estrogens, while loss of expression of estrogen receptor … common step in the development
of colorectal cancer (CRC). … of estrogen receptor beta (ESR2) for cancer risk, but relevant …
of colorectal cancer (CRC). … of estrogen receptor beta (ESR2) for cancer risk, but relevant …
[HTML][HTML] Expression of estrogen receptor β in human colorectal cancer
LQ Xie, JP Yu, HS Luo - World Journal of Gastroenterology, 2004 - ncbi.nlm.nih.gov
… shown that the risk of colorectal cancer is reduced among postmenopausal hormone users,
… Animal models showed that male rats had a higher risk developing colon cancer compared …
… Animal models showed that male rats had a higher risk developing colon cancer compared …
Molecular pathways: estrogen pathway in colorectal cancer
A Barzi, AM Lenz, MJ Labonte, HJ Lenz - Clinical cancer research, 2013 - AACR
… The estrogen receptor (ER) recognizes a molecule as estrogen based on its three-dimensional
configuration and charge, but preferentially binds E2 over E3 (2×) and E1 [3× (ref. 9)]…
configuration and charge, but preferentially binds E2 over E3 (2×) and E1 [3× (ref. 9)]…
Estrogen receptor‐β gene polymorphism and colorectal cancer risk: Effect modified by body mass index and isoflavone intake
N Honma, K Yamamoto, K Ohnaka… - … journal of cancer, 2013 - Wiley Online Library
… this polymorphism and the colorectal cancer risk in a community-… The risk of colon cancer,
but not of rectal cancer, was … Increased risks of colon cancer associated with the L allele were …
but not of rectal cancer, was … Increased risks of colon cancer associated with the L allele were …
[HTML][HTML] Estrogen receptors in colorectal cancer: Facts, novelties and perspectives
I Ditonno, G Losurdo, M Rendina, M Pricci, B Girardi… - Current …, 2021 - mdpi.com
… colon cancer cells with ERβ gene constructed into adenoviral vectors alone or in combination
with raloxifene, a selective estrogen receptor … agent in HCT116 colon cancer cells by …
with raloxifene, a selective estrogen receptor … agent in HCT116 colon cancer cells by …
[HTML][HTML] Expression of oestrogen receptor β and prognosis of colorectal cancer
A Rudolph, C Toth, M Hoffmeister, W Roth… - … journal of cancer, 2012 - nature.com
… Previous studies suggest that sex steroids influence colorectal cancer (CRC) carcinogenesis.
The oestrogen receptor β (ERβ) is the predominantly expressed ER in the colon and loss …
The oestrogen receptor β (ERβ) is the predominantly expressed ER in the colon and loss …
Expression of estrogen receptor β in colon cancer progression
F Castiglione, A Taddei… - Diagnostic Molecular …, 2008 - journals.lww.com
… Moreover, we evaluate a possible correlation between estrogen's receptor expressions and
… estrogen receptor β expression greater than pathologic tissues and the estrogen receptor β …
… estrogen receptor β expression greater than pathologic tissues and the estrogen receptor β …
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