… The estrogen receptor (ER) recognizes a molecule as estrogen based on its three-dimensional
configuration and charge, but preferentially binds E2 over E3 (2×) and E1 [3× (ref. 9)]…

… gamma (ESRRG), the NR3B subfamily of nuclear receptors, is characterized by a significant
homology similarity with the classical estrogen receptors at the amino acid level, and is …

… expression of the ER but increased estrogenic activity, for example. The cloning of ER-β
provided an example of a steroid hormone receptor … Human ER-β is localized on chromosome …

… In summary, estrogen receptor β has recently received more interest as a promising targeted
therapy for colorectal cancer, as it affects multiple pathways and the expression of a wide …

… expression of miR-135b was inversely correlated with serum E 2 level and ER-β mRNA
expression in CRC patients' cancer … expression of ER-β, miR-135b, and MMR in colon cancer …

… tumors negative for estrogen receptor α. The clinical significance of ER-B expression in tumors
… The case of colon cancer in this example shows only nuclear staining for ER-B (B), while …

… A large number of studies have suggested an inhibitory role of estrogens against colorectal
cancer (CRC), but persistent controversy exists. CRC characteristics are affected by sex, age…

… NLRP3 was differentially expressed in normal and colon cancer cells, while … expression,
suppress colon cancer cells proliferation and promote apoptosis by inhibited NLRP3 expression …

… Using RT-PCR we found that the oestrogen receptor α (ERα) … Figure 3 ER expression in
colon cancer cell lines. Total RNA … (A) ERα expression in colon cancer cell lines detected by RT-…

… Loss of estrogen receptor β (ERβ) expression in the gut is associated with colorectal cancer
… ) in genes for the sex-steroid hormone receptors are not strongly associated with CRC risk; …