… Due to the relative shortage of data concerning ERβ expression in colon cancer, there is no
consensus cut-off level to distinguish positive from negative cases. A cut-off level of 10% was …

… Oestrogen receptor β (ERβ) has been suggested to have anti-proliferative and anti-tumour
effects in breast and prostate cancer … Understanding the complex effects of this receptor in …

… that ERβ is the predominant ER expressed in colonic tissues (15, 16), that the ERβ gene is
methylated in 90% of colon cancer tissues (17), and that expression of ERβ is selectively lost …

… the two estrogen receptor subtypes, estrogen receptor ERa and ERb,12 the tissuespecific
role of estrogen, dependent on the receptor … ERb is the predominant receptor in the gut and is …

… Notably, UC and CD are associated with an increased risk of colorectal cancer (CRC) that
appears to increase with the duration, severity and anatomic extent of colonic inflammation [24…

… In this experimental setting we not only evaluated the relationship between intestinal polyp
development and ER-β expression but assessed epithelial cell proliferation, apoptosis, and …

… Estrogen receptor (ER)-β signaling has generally been implicated in protection against
colorectal cancer. The ER-β gene cytosine-adenine (ESR2 CA) repeat polymorphism was …

… prognostic impact of tumor cell expression of hormone receptors combining with other host …
prognostic impact of tumor cell expression of hormone receptors in terms of local relapse-free …

… Estrogen hormones protect against colorectal cancer (CRC) and a preventative role of
estrogen receptor beta … To investigate the functional role of intestinal ERβ during colitis-associated …

… main isoform expressed in colon we … expression effect on CRC cells proliferation and
expression of oncogenes or tumor suppressors, revealing it protective role [13]. For example, ER-β …