Estrogen receptor β potentiates the antiproliferative effect of raloxifene and affects the cell migration and invasion in HCT-116 colon cancer cells
Z Tu, Y Ma, J Tian, H Li, W Akers, S Achilefu… - Journal of cancer …, 2012 - Springer
… Estrogen receptor β (ERβ) is the predominant ER in the colorectal epithelium, whose
expression is greatly … (ER) isoform involved in E2 protection against colorectal cancer. Since …
expression is greatly … (ER) isoform involved in E2 protection against colorectal cancer. Since …
Preliminary study on the expression of Estrogen Receptor Beta (ERβ) in colorectal carcinoma
MX Keh, A Azmahani, H Faroque… - Asian Journal of …, 2020 - journal.unisza.edu.my
… development of colorectal cancer treatments. It is therefore believed that estrogen-mediated …
Hence, the purpose of this study was to determine the expression of estrogen receptor beta (…
Hence, the purpose of this study was to determine the expression of estrogen receptor beta (…
Gene signatures of estrogen and progesterone receptor pathways predict the prognosis of colorectal cancer
D Liu - The FEBS journal, 2016 - Wiley Online Library
… The associations of estrogen receptor (ER) and progesterone receptor (PR) pathways with
the prognosis of colorectal cancer (CRC) are still controversial. The aim of this study was to …
the prognosis of colorectal cancer (CRC) are still controversial. The aim of this study was to …
Oestrogen and colorectal cancer: mechanisms and controversies
PA Foster - International journal of colorectal disease, 2013 - Springer
… The role of oestrogen metabolism and action in colorectal cancer (CRC) is controversial. An
… Evidence also suggests that protective effects are modulated through oestrogen receptor …
… Evidence also suggests that protective effects are modulated through oestrogen receptor …
Estrogen metabolism in human colorectal cancer cells
G Fiorelli, L Picariello, V Martineti, I Tognarini… - The Journal of Steroid …, 2002 - Elsevier
… In the present study, the CRC estrogen receptor β (ERβ) positive HCT8, HCT116, DLD-1
and LoVo cell lines were evaluated for expression of functional 17β-hydroxysteroid …
and LoVo cell lines were evaluated for expression of functional 17β-hydroxysteroid …
17β-estradiol in colorectal cancer: friend or foe?
Z Wu, C Xiao, J Wang, M Zhou, F You, X Li - Cell Communication and …, 2024 - Springer
… As the most potent estrogen, E2 mediates its effects by binding to nuclear estrogen
receptors (ERα, ERβ) and the membrane-associated G protein-coupled estrogen receptor (GPER). …
receptors (ERα, ERβ) and the membrane-associated G protein-coupled estrogen receptor (GPER). …
[PDF][PDF] A novel shift in estrogen receptor expression occurs as estradiol suppresses inflammation-associated colon tumor formation
CM Armstrong, AR Billimek, KF Allred… - … Relat Cancer, 2013 - researchgate.net
… Jiang H, Teng R, Wang Q, Zhang X, Wang H, Wang Z, Cao J & Teng L 2008 Transcriptional
analysis of estrogen receptor a variant mRNAs in colorectal cancers and their matched …
analysis of estrogen receptor a variant mRNAs in colorectal cancers and their matched …
The biological role of estrogen receptors α and β in cancer
ST Pearce, VC Jordan - Critical reviews in oncology/hematology, 2004 - Elsevier
… of estrogen are mediated by estrogen receptors α and β. The ERs are steroid hormone receptors
… prevention of breast, prostate and colon cancer is a result of a higher incidence of these …
… prevention of breast, prostate and colon cancer is a result of a higher incidence of these …
Estrogen receptor α variant ERα46 mediates growth inhibition and apoptosis of human HT-29 colon adenocarcinoma cells in the presence of 17β-oestradiol
H Jiang, R Teng, Q Wang, X Zhang, H Wang… - Chinese medical …, 2008 - mednexus.org
… In this study,we compared the expression of ERa46 mRNA in 32 normaI colorectal tissues
and their matched colorectal cancer … suggest that estrogen plays a role in colorectal cancer …
and their matched colorectal cancer … suggest that estrogen plays a role in colorectal cancer …
Estrogen receptor beta influences the inflammatory p65 cistrome in colon cancer cells
R Indukuri, L Hases, A Archer, C Williams - Frontiers in endocrinology, 2021 - frontiersin.org
… Inflammation is a primary component of both initiation and promotion of colorectal cancer
(CRC). Cytokines secreted by macrophages, including tumor necrosis factor alpha (TNFα), …
(CRC). Cytokines secreted by macrophages, including tumor necrosis factor alpha (TNFα), …