… estrogen receptor beta (ERβ/ESR2) demonstrates an inverse relationship with the presence
of colorectal … of colorectal adenomatous polyps and prevention of colorectal carcinoma in …

… Abnormal estrogen receptor signaling may increase the risk of development of a variety of
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …

… The estrogen receptor (ER) recognizes a molecule as estrogen based on its three-dimensional
configuration and charge, but preferentially binds E2 over E3 (2×) and E1 [3× (ref. 9)]…

… of target tissues, estrogen molecules diffuse into cytoplasm, and bind to estrogen receptors,
then … The estrogen receptor discovered in 1986 is named ERα, and another ER subtype …

… alter the structural organization and DNA binding of estrogen receptors in a dose-dependent
manner [… For example, estradiol binding to the receptor and the affinity of the ligand-receptor …

… role for estrogens has been hypothesized. Indeed, two isoforms of nuclear estrogen receptors
(ER) … While the binding of 17beta-estradiol to ERα activates anti-apoptotic pathways, the …

… Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal cancer (CRC). …
and development of CRC when activated by estrogen. Further studies are needed to …

… that estrogen replacement therapy (ERT) reduces cancer risk in … Colorectal (colon) cancer
is the second most common cause … Estrogen replacement therapy and colorectal cancer risk in …

… avenue in colorectal cancer, we report the most recent experimental evidence to explain
the cellular and molecular mechanisms of estrogen-mediated protection against colorectal …

… colon cancer cell lines and tumors 1 and estradiol was found to activate the growth of colon
cancer cell line in vitro,2, 3 an estrogen receptor has not been detected in human colorectal …