… estrogen replacement therapy on colon cancer. The estrogen receptor (ER) is required for the
action of estrogen… and transcriptional response to selective estrogen response modulators. …

… the estrogen receptor, agents displaying this tissue selective profile were later classified as
selective estrogen receptor … The effects of various estrogenic agents at preventing bone loss …

… estrogen that are mediated through the estrogen receptor (ER). However, these drugs also
have many estrogenic … are more appropriately called selective estrogen receptor modulators (…

Selective estrogen receptor modulators (SERMs) are synthetic non-steroidal agents which
have variable estrogen agonist and antagonist activities in different target tissues. Tamoxifen …

… an estrogen agonist or an antagonist. More recently we have learnt that there are two estrogen
receptors which… bone loss have been published and the results look good [18’]. Raloxifen …

… site-specific actions of the selective estrogen receptor modulators tamoxifen and raloxifene.
The known beneficial or negative actions of selective estrogen receptor modulators (SERMs) …

Professor Paul Ehrlich is the father of experimental chemotherapy. During the first decade of
the 20th Century, he reasoned that compounds could be synthesized to exhibit selective …

… Selective estrogen receptor modulators (SERMs) are a diverse group of nonsteroidal
compounds that function as agonists or antagonists for estrogen receptors (ERs) in a target gene-…

… estrogen receptor α (ERα) in mediating estrogen-dependent bone maintenance in female
mice. We selectively … , but not males, exhibited trabecular bone loss, similar to the osteoporotic …

… referring to the molecular biology of estrogen receptor. Clinical trials are conducted with …
in risk for estrogen receptor-negative tumors. Selective estrogen receptor modulators might …