Over the past two decades, we have learned that estrogens play important physiological roles
not only in women but also in men and that the biological effects of estrogen are mediated …

… Determining ER subtypes expression may improve response to hormonal therapy by
tailoring the use of selective estrogen receptor modulators with different ER affinity in selected …

… least three subtypes of estrogen receptor (ESR), ESR1, ESR2a, and ESR2b; thus, estrogenic
… to investigate the ESR subtype-specificity for better understanding the signaling pathway of …

… on various estrogen target tissues. 6 Thus, the net effect of estrogens depends not only on
the level of ER expression, but also on the relative distribution of the 2 receptor subtypes. 7 …

… of estrogen receptor subtype agonists (ERSAs) for drug therapy. Potential ERβ-selective
estrogens… regulation of genes with different classes of estrogen receptor beta-selective agonists …

… of estrogen receptors (ERs) within these tissues is an area of controversy. ERs exist as two
subtypes … ER expression and estrogen sensitivity may result from differential expression of ER …

… Estrogen receptors (ERs) control transcription of genes … understanding of the roles of receptor
subtypes ERα and ERβ in … The 2,3-diarylindenes bind with high affinity to the ER subtypes …

… The physiological actions of estrogens in regulating gene transcription are mediated through
the estrogen receptor (ER). The identification of a second “type” of ER, named ERβ, in rats (…

… the variety of estrogen receptor subtypes that exist, but also because many subtypes have
… roles that specific estrogen receptor subtypes play in mediating estradiol's anorexigenic and …

… estrogen receptor subtypes ERα and ERβ in HeLa cells. Cells co-transfected with an estrogen
… displayed a small but significant estrogenic activity via ERα, whereas it was a complete …