… of estrogens on colon cancer risk. Given the scarcity of information regarding ER mRNA
expression levels in human colon, … colon carcinoma cells and cultured cells from normal colonic …

… organization and DNA binding of estrogen receptors in a dose-… For example, estradiol
binding to the receptor and the affinity … proportion of human breast and colon carcinoma [124,125]. …

… of estrogens against carcinogenesis specifically in the colon was the subject of a previous
review (3). Here, we aim to extend our analysis of estrogen signaling in the colon… the estrogen …

… by treating HCT116 colon cancer cells with ERβ gene constructed into adenoviral vectors
alone or in combination with raloxifene, a selective estrogen receptor modulator. Only the …

… Abnormal estrogen receptor signaling may increase the risk of development of a variety
of … Estrogen receptor beta (ERβ) is the predominant subtype in the colonic epithelium and …

… of estrogen receptor (ER); the results of this study are reported in Table 2. Estrogen receptors
… wet colon. The binding capacity of cER in cancerous tissue ranged from 118 to 1213 fmol/g …

… the published data on estrogen receptors in healthy and malignant colonic tissue, and …
In colon carcinoma cell lines, the expression of the classical ERα has not been detected but …

… effects on the colonic mucosa (5–7). In the human colonic epithelium, estrogen receptor β
(ERβ) … The ERs mediate their effects by binding to estrogen response elements (ERE) in gene …

… In this review, we discuss the roles of estrogen receptors and their multiple molecular
targets in CRC pathogenesis. We also outlined the use of some potential natural or synthetic …

… colon cancer cell lines and tumors 1 and estradiol was found to activate the growth of colon
cancer cell line in vitro,2, 3 an estrogen receptor … in human colorectal carcinomas (CRCs) by …