The Triad of Estrogen, Estrogen Receptors, and Colon Cancer

KR Sumalatha, S Soumyakrishnan… - Colon Cancer Diagnosis …, 2022 - Springer
… effects of estrogen. Reduced expression of the nuclear estrogen receptor beta in the colon
is … In vitro studies on carcinoma cell lines and in vivo studies on mouse models have proven …

Estrogen and cancers of the colorectum, breast, and lung in postmenopausal women

N Honma, T Hosoi, T Arai, K Takubo - Pathology international, 2015 - Wiley Online Library
estrogens plays major roles in the female reproductive organs through the classic estrogen
receptor, … shown that estrogen concentrations were higher in colon carcinoma tissues than in …

Expression of estrogen receptor β1 in colorectal cancer: Correlation with clinicopathological variables

L Rath-Wolfson, O Purim, E Ram… - Oncology …, 2012 - spandidos-publications.com
… Our study demonstrated that the ERβ1 expression in the nuclei of the tumor cells was
significantly higher in colon carcinoma cases of those patients who died of the disease and …

[HTML][HTML] G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

D Jacenik, EJ Beswick, WM Krajewska… - World Journal of …, 2019 - ncbi.nlm.nih.gov
… α and β, as well as the membrane-bound G protein-coupled estrogen receptor (GPER). The
… GPER in the colon have shown that this estrogen receptor regulates colonic motility as well …

The roles of estrogen and estrogen receptors in gastrointestinal disease

C Chen, X Gong, X Yang, X Shang… - Oncology …, 2019 - spandidos-publications.com
Estrogen exhibits various functions through binding to its specific receptors, estrogen receptor
α, estrogen receptor … ERβ is encoded by estrogen receptor 2 or estrogen receptor 2, which …

Molecular study of sex steroid receptor gene expression in human colon and in colorectal carcinomas

P Waliszewski, M Blaszczyk… - Journal of surgical …, 1997 - Wiley Online Library
estrogen receptors in human colon carcinoma and in surrounding noncancerous colonic
tissue. Gastroenterology 93:1301–1306, 44. GreeneGL,GilnaP,WaterfieldM,etal.:…

Sex-specific differences in the expression levels of estrogen receptor subtypes in colorectal cancer

NC Nüssler, K Reinbacher, N Shanny, A Schirmeier… - Gender medicine, 2008 - Elsevier
estrogen receptor alpha (ERe0 and beta (ERI3) protein in samples of macroscopically normal
colon … Selective loss of estrogen receptor I 3 in malignant human colon. Cancer Res. 2000;…

Selectively targeting estrogen receptors for cancer treatment

EK Shanle, W Xu - Advanced drug delivery reviews, 2010 - Elsevier
Estrogens regulate growth and development through the action of two distinct estrogen
receptors (… For decades, ERα mediated estrogen signaling has been therapeutically targeted to …

An immunohistochemical study with an estrogen receptor‐related protein (ER‐D5) in human colorectal cancer

H Takeda, M Yamakawa, T Takahashi, Y Imai… - Cancer, 1992 - Wiley Online Library
estradiol in human colon cancer tissue^.'^ In the current study, to investigate the presence of
the estrogen receptor in colon … cytosolic estrogen receptors in human colon carcinoma and …

Estrogen receptors, estrogens and colon cancer

F Al-Azzawi - Hormone Replacement Therapy and Cancer, 2020 - taylorfrancis.com
… In colon carcinoma cell lines the expression of classical ERa has not been detected, but
four functional isoforms of ER~, in terms of bind ing to 17{Hstradiol, have been documented. …