Colorectal cancer risk associated with hormone use varies by expression of estrogen receptor

A Rudolph, C Toth, M Hoffmeister, W Roth, E Herpel… - Cancer research, 2013 - AACR
estrogen effects is the estrogen receptor-β (ESR2), which is the primarily expressed estrogen
receptor … ), as high levels of endogenous estrogens have been found to be associated with …

Estrogen and progesterone binding proteins in human colorectal cancer. A preliminary characterization of estradiol receptor

V Sica, E Contieri, E Nola, R Bova, G Papaleo… - Tumori …, 1981 - journals.sagepub.com
Estradiol receptor (ER) and progesterone receptor (PgR) were assayed in tumors from 20
… of colon adenocarcinoma (l ml) were incubated at 4 C for 4 h with 6 nM [3H]estradiol in the …

[HTML][HTML] Estrogen, estrogen receptors, and hepatocellular carcinoma: Are we there yet?

OA Sukocheva - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
… However, it remains to be identified how to exploit estrogenestrogen pathway in liver cells.
The main problems include the absence of a clear understanding of which estrogen receptor (…

Estrogen receptors and human disease

BJ Deroo, KS Korach - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
… induce overlapping but distinct sets of genes in both cells from type I endometrial carcinoma
… expression after estradiol and tamoxifen treatment of endometrial carcinoma cells but not …

Presence of somatomedin receptors on primary human breast and colon carcinomas

MN Pollak, JF Perdue, RG Margolese, K Baer… - Cancer letters, 1987 - Elsevier
… IGF-I receptor-positive cancers may exhibit a dependance on exogenous IGF-I for optimum
proliferation, in a manner analogous to estrogen dependance of estrogen-receptor-… in colon

Positive expression of estrogen receptor alpha correlates with poor prognosis and metastasis in colorectal cancer

G Topi, SR Satapathy, RR Ehrnström, ML Lydrup… - Cancer Research, 2020 - AACR
receptor in the normal colon mucosa, and its expression is downregulated in colorectal … the
normal colon tissue. An increased ERα/β ratio has been shown in colon carcinomas. However…

Ligand‐dependent interaction between estrogen receptor α and adenomatous polyposis coli

AP Kouzmenko, K Takeyama, Y Kawasaki… - Genes to …, 2008 - Wiley Online Library
… effects of estrogens are predominantly mediated by the action of nuclear estrogen receptors
(… Human colon carcinoma SW480 and CACO2 cells express only truncated APC (1–1338) …

Estrogen receptor α/β, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?

PD Grivas, V Tzelepi, G Sotiropoulou-Bonikou… - International journal of …, 2009 - Springer
estrogen receptor–coactivator first described in breast adenocarcinomas. It is a member
of the p160 family of estrogen receptor … tissue, implying that colon carcinoma cells may be …

[HTML][HTML] Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205-PROX1 mechanism

T Nguyen-Vu, J Wang, F Mesmar, S Mukhopadhyay… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colon cancer is a common cause of cancer death in the Western world. Accumulating
evidence supports a protective role of estrogen via estrogen receptor beta (ERβ) but the …

The sharp decline of beta estrogen receptors expression in long-lasting ulcerative-associated carcinoma

M Principi, MP Scavo, D Piscitelli… - Scandinavian Journal …, 2015 - Taylor & Francis
… presence of two types of estrogen receptors (ERs) alpha and beta and their distribution
changes in adenomas and CRC [Citation15,16] suggests that estrogens may have a direct role in …