… of estrogens on colon cancer risk. Given the scarcity of information regarding ER mRNA
expression levels in human colon… may mediate estrogenic effects on colon cancer susceptibility. …

… These evidences suggest that estrogen maybe involved in the growth of colonic tumors.
Estrogen receptor locates at the cellular nuclei of target tissues, estrogen molecules diffuse into …

… Estrogen receptor β (ER-β) has recently been detected in a human colon cancer cell line. …
whether ER-β is expressed in human colorectal carcinoma (CRC) tissue and the extent of this …

… Human colon cancer tissue and adjacent normal colon tissue … colon resection for colon
cancer. Western blot analysis revealed very low levels of ER-α protein in tumor and normal colon …

… intestinal tumors, a possible relationship between estrogens and human colorectal tumors
… Subsequently, the presence of estrogen receptors (ERs) was reported in these tumors [35]. …

… pathway as a possible therapeutic avenue in colorectal cancer, … , including the role of
the tumor microenvironment and … the estrogen pathway as a therapy in colorectal cancer (CRC). …

… estrogen receptor (cER) and nuclear estrogen receptor (nER) in the tissue of 26 human
colorectal … presence of estrogen receptor (ER); the results of this study are reported in Table 2. …

… differentiates between binding to free estrogen receptor sites and sex steroid binding … in
patients with colon cancer as in routinely applied to patients with disseminated breast cancer. Per…

… estrogen receptors in colorectal cancer cells provides the basis for the existence of an autocrine
mechanism for estrogen in the neoplastic progression of colon cancer. … of colon cancer …

… that additional human colon cancer cell lines were … colon cancer cells appeared to express
ERß mRNA. Since the presence of estrogen receptors has been demonstrated in the human …