Biological Activities of Euphorbia peplus Leaves Ethanolic Extract and the Extract Fabricated Gold Nanoparticles (AuNPs)

HA Ghramh, KA Khan, EH Ibrahim - Molecules, 2019 - mdpi.com
… HepG2 and Hela cells, while EpExt inhibited HepG2 but stimulated HelaEuphorbia peplus
leaves ethanol extract (EpExt-AuNPs) showed inhibitory effects against HepG2 and Hela cells

… -hopane type triterpenoids from Euphorbia peplus with simiarendiol possessing significant cytostatic activity against hela cells by induction of apoptosis and S/G2 cell …

JH Yu, DX Wu, ZP Yu, YP Li, YY Wang, SJ Yu, H Zhang - Molecules, 2019 - mdpi.com
HeLa cells in a dose-dependent manner. We also explored whether simiarendiol (2) led to
a cell cycle arrest in the HeLa cells … phases of the cell cycle, as the percentages of cells at S/…

Cytotoxicity of Euphorbia peplus extract on MCF7 breast cancer cells

A Al-Emam, M Al-Shraim, RA Eid… - Folia Biologica …, 2019 - ingentaconnect.com
… In summary, Euphorbia peplus has displayed growth inhibitory activity against MCF7 cells
and induces cell death predominantly via apoptosis and could be exploited as a breast cancer …

Three new diterpenoids from Euphorbia peplus

YN Chen, QY Lu, DM Li, YY Li, XX Pu, BT Li… - Natural Product …, 2021 - Taylor & Francis
… , HeLa cells with 85% cell density in 96-well plates were treated with individual compounds
at 40 μM in triplicate. Three hours later, cells … to validation by treating HeLa cells with two …

Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis

YN Chen, X Ding, QY Lu, DM Li, BT Li, S Liu, L Yang… - Bioorganic …, 2020 - Elsevier
… In order to investigate whether compound 1 activates mTORC1, we treated HeLa cells with
20 μM compound 1 and checked the activity of mTORC1. The level of p-S6K in the mTOR …

Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway

YN Chen, X Ding, DM Li, QY Lu, S Liu, YY Li… - Natural Products and …, 2021 - Springer
… CFP-LC3 expressing HeLa cells were treated with indicated compounds and images were
collected by confocal microscopy. For live-cell imaging, cells grown on glass-bottom dishes …

[PDF][PDF] Estimation of toxic hazards caused by methanolic extract of Euphorbia peplus in male albino rats

G Moustafa, A Mohammed… - Adv. Anim …, 2016 - nexusacademicpublishers.com
Euphorbia spp., little has paid any attention to the adverse effects of different plants of genus
Euphorbia especially Euphorbia peplus … investigate the toxic impacts of Euphorbia peplus. …

Investigation into two Australian medicinal plants Viola odorata and Euphorbia peplus for anticancer agents

SF Fernando - 2002 - vuir.vu.edu.au
… to explain the purported in vivo anticancer activity of Euphorbia peplus L. and Viola odorata
L. … shown arrest of HeLa cells in mitosis by dissolution of the mitotic spindle. Cells exposed to …

Diterpenoids from Euphorbia peplus possessing cytotoxic and anti-inflammatory activities

Y Li, ZP Yu, YP Li, JH Yu, JM Yue - Bioorganic Chemistry, 2024 - Elsevier
… Simiarendiol, a new isolate, shows significant inhibitory activity against the proliferation
of HeLa cells through induction of apoptosis and cell cycle arrest at S/G2 phases in a dose-…

Inhibition of tumor cells growth and stimulation of lymphocytes by Euphorbia species

Z Amirghofran, S Malek-hosseini… - …, 2011 - Taylor & Francis
… This extract was mostly effective on Hela cells with IC 50 of 70 μg/ml. The IC 50 obtained for
… on Hela cells except hexane was more than 200 μg/mL. 50% growth inhibition of Hela cells