The incidence of hepatocellular carcinoma (HCC) is increasing in the United States and is
predicted to continue to increase. 1 Over the last several decades, the escalation in HCC
has mirrored the increase in the incidence of hepatitis C virus (HCV)-induced cirrhosis,
which carries the highest risk for the development of HCC, at an estimated 2% to 8% per
year. The peak incidence of HCV-induced HCC is projected to occur in 2020. Despite an
anticipated decline in HCV-induced cirrhosis and hence HCC, HCC related to nonalcoholic …