The present study describes compatibility of anti-HIV drug lamivudine with various selected
excipients and a novel synthesized polymer, for the development of its controlled release
formulation. Differential scanning calorimetry (DSC), isothermal stability study (ISS) and
Fourier transform infrared (FT-IR) spectral analysis were performed to access the
compatibility. The compatibility study was performed with various common excipients like
spray dried lactose, polyvinyl pyrrolidine K-30, magnesium stearate, talc and a novel …

The compatibility between albendazole and closantel, with commonly used tablet excipients,
was assessed by studying drug-excipient mixtures mixed in 1: 1 ratio and 1: 1 ratios
granulated with water and dried at 50° C for 1 hr with a differential scanning calorimeter
(DSC) and high-performance liquid chromatograph (HPLC). Results showed that there were
interactions between closantel and/or albendazole and some tablet excipients. For example,
magnesium stearate reacted with both drugs and the interaction was observed by DSC and …