… We here report the synthesis and biological evaluation of new phenylcarbazole derivatives
designed as potential anticancer agents. Indole and hydroxyindole were used to generate …

Drugs that inhibit DNA topoisomerase I and DNA topoisomerase II have been widely used
in cancer chemotherapy. We report herein the results of a focused medicinal chemistry effort …

… novel anticancer agents in the naphthalenic series. … vivo evaluations. The efficient synthetic
routes reported here provides novel opportunities to design DNA-targeted antitumor agents. …

… A new series of novel pyrrolizine derivatives has been synthesized and biologically
evaluated as potential anticancer agents. The starting compounds, 6-amino-7-cyano-N-(3,5-…

… , a series of new sulfonamides as potential anticancer drugs were rationally designed by …
inhibition activity of novel sulfonamides as potential anticancer agents were created using the …

… development into potential anticancer agents. … possible molecular mechanisms involved
in the anticancer activity of our compounds and to evaluate their chemotherapeutic potential in …

… A series of novel ursolic acid (UA) derivatives modified at the C-3 and the C-28 positions …
to develop potential antitumor agents. The in vitro cytotoxicity were evaluated against five …

… for discovery of new drugs have been an attractive field in medicinal chemistry. In our efforts
to search for novel antitumor agents, we have designed and synthesized a novel type of …

… We report the synthesis and biological evaluation of new oxophenylarcyriaflavins designed
as potential anticancer agents. An efficient synthesis involving palladium-catalyzed Suzuki …

… New anticancer agents are highly needed to overcome cancer cell resistance. A novel
series of pyrimidine pyrazoline-anthracene derivatives (PPADs) (4a-t) were designed and …