Development and evaluation of vancomycin dosage guidelines designed to achieve new target concentrations

AH Thomson, CE Staatz, CM Tobin… - Journal of …, 2009 - academic.oup.com
… and evaluation datasets in terms of patients' initial SeCr values, initial vancomycin dose,
vancomycin concentration values or the length of time after the start of infusion that vancomycin

Multicenter evaluation of vancomycin dosing: emphasis on obesity

RG Hall II, KD Payne, AM Bain, AP Rahman… - The American journal of …, 2008 - Elsevier
dose was changed within 24 hours (if initially inappropriate). The site of infection and vancomycin
drug concentrations were not evaluated, … weight-based vancomycin dosing practices. …

Evaluation of vancomycin dosing and monitoring in adult medicine patients

S Devabhakthuni, JP Gonzales, AL Tata… - Hospital …, 2012 - journals.sagepub.com
… For evaluation in this study, trough concentrations were considered … vancomycin dose.
The 1 hour after the scheduled vancomycin dose time period was only used when the dose was …

Vancomycin dosing and monitoring: critical evaluation of the current practice

F Elbarbry - European journal of drug metabolism and …, 2018 - Springer
… This review critically discusses the current guidelines of vancomycin dosing and monitoring,
… based dosing strategies (nomograms) to improve the efficiency of vancomycin dosing while …

Evaluation of vancomycin dosing and corresponding drug concentrations in pediatric patients

LM Geerlof, J Boucher - Hospital pediatrics, 2014 - publications.aap.org
… This analysis evaluated 3 different dosing regimens: 15 mg/kg per dose every 6 hours,
20 mg/kg per dose every 8 hours, and 15 mg/kg per dose every 8 hours. The trough …

An evaluation of vancomycin dosing for complicated infections in pediatric patients

SH Durham, ML Simmons, DW Mulherin… - Hospital …, 2015 - publications.aap.org
Objective: To determine the incidence with which a vancomycin dosing regimen of 15 mg/kg
per dose every 6 hours achieves steady-state trough concentrations of 15 to 20 mg/L in …

Vancomycin Utilization Evaluation: Are We Dosing Appropriately?

L Ayazkhoo, S Mousavi, F Ramazani… - Journal of …, 2013 - jpc.tums.ac.ir
… Our results suggest that vancomycin dosing is often empiric and … doses of vancomycin due
to fear of its potential nephrotoxicity. Data derived from more recent studies and vancomycin

Evaluation of vancomycin dosing regimens in preterm and term neonates using Monte Carlo simulations

N Mehrotra, L Tang, SJ Phelps… - … : The Journal of Human …, 2012 - Wiley Online Library
… using a simulation-based evaluation. Five thousand subjects … simulation was to evaluate
vancomycin dosing regimens in … on the predictions to evaluate whether they correspond with …

Evaluation of three methods for determining initial vancomycin doses

BH Ackerman - 1989 - journals.sagepub.com
… the six-hour dosing interval was the most successful method for initial dose selection, but …
-derived doses is necessary to assure safe and effective vancomycin serum concentrations. …

Outcome assessment of minimizing vancomycin monitoring and dosing adjustments

CM Karam, PS McKinnon… - … : The Journal of …, 1999 - Wiley Online Library
… monitoring of peak and trough concentrations of vancomycin is not trivial. Time and motion
studies indicated that the time spent evaluating vancomycin regimens was 371.7 hours for …