… In this review, we highlight the gaps for which we need old antibiotics in community- and …
Summarising older evidence shows the inferiority of chloramphenicol versus modern antibiotics …

… Misuse often goes with diagnostic uncertainty and delayed prescription can be a preferred
option but we lack evidence on the efficacy of eg antibiotic cycling and combination therapy. …

… failure (additional or change in antibiotic treatment due to UTI or discontinuation due to
lack of efficacy) or indeterminate (persistent symptoms without evidence of UTI). Secondary …

… of both broad-spectrum- and old, narrowspectrum antibiotics the last few years, leaving
us with fewer treatment options 48. Old antibiotics may give limited return of investment for …

… During stent indwell time, antibiotic prophylaxis does not show any advantage in … evidence
to support the use of antibiotics at time of stent removal. In the absence of any clear evidence, …

… An overview of the shortage of data for selected old antibiotics … evidence, a redevelopment
procedure for old antibiotics is … for the knowledge and evidence gaps. First, although the …

… new antibiotics has declined while antibiotic resistance … antibiotics in order to preserve
newer antibiotics and to slow down development of resistance. In order to optimise use, evidence …

… antibiotic use and ABR in the human and animal population in the national context, and to
then develop evidence-… and use of antibiotics at the national level, the GAP builds on existing …

… documenting the effectiveness of interventions to improve veterinary prescribing, this review
has identified some gaps in the human evidence. Studies in hospitals were most common, …

… only aid clinicians in their choice of empirical antibiotic treatment, but also support … antibiotic
resistant pathogens within different patient settings in Switzerland, to identify screening gaps …