Origins and evolution of antibiotic resistance

J Davies, D Davies - Microbiology and molecular biology reviews, 2010 - Am Soc Microbiol
… of antibiotics to exploit every source of resistance genes and … of resistance for each and
every antibiotic introduced into … salient aspects of antibiotic resistance development over the …

Evolution of antibiotic resistance

F Baquero, J Blázquez - Trends in ecology & evolution, 1997 - cell.com
… The origin of these resistance mechanisms remains an open evolutionary questionr. Genes
… in antibiotic resistance have probably evolved for other purposes than antibiotic resistance. …

The evolution of antibiotic resistance

RC MacLean, A San Millan - Science, 2019 - science.org
… for bacterial infections, and antibiotics have since had huge effects on … antibiotic resistance
(ABR): Many pathogenic bacteria have evolved resistance to the main classes of antibiotics

Ecology and evolution of antibiotic resistance

F Baquero, C Alvarez‐Ortega… - Environmental …, 2009 - Wiley Online Library
… Along this article, we will discuss some aspects of antibiotic resistance related to the
basic mechanisms of evolution. In this regard, in contrast with the situation with Metazoans (Navas …

The evolution of antibiotic resistance

F González-Candelas, I Comas, JL Martínez… - Genetics and Evolution …, 2011 - Elsevier
… as selection for antibiotic-resistant organisms and a faster evolution of antibiotic resistance.
… , human, farming, and agricultural, so that the antibiotic-derived effects in one of them has …

Origins and evolution of antibiotic resistance.

J Davies - Microbiología (Madrid, Spain), 1996 - europepmc.org
… The massive prescription of antibiotics and their non-regulated and extensive … antibiotic
resistance in microorganisms; this has been of great clinical significance. Antibiotic resistance

[HTML][HTML] Inhibiting the evolution of antibiotic resistance

MN Ragheb, MK Thomason, C Hsu, P Nugent, J Gage… - Molecular cell, 2019 - cell.com
… factor, the absence of which hinders antibiotic resistance development. We show that Mfd …
multiple classes of antibiotics. We also find that Mfd promotes the evolution of hypermutation, …

Evolution of antibiotic resistance gene function

AL Koch - Microbiological Reviews, 1981 - Am Soc Microbiol
… Of course, resistance based on transmissible plasmids affords the significant … : (i) resistance
to several antibiotics can be be brought together in single plasmids; (ii) antibiotic resistance

Evolution and spread of antibiotic resistance

BH Normark, S Normark - Journal of internal medicine, 2002 - Wiley Online Library
… for antibiotic resistance and the parameters involved in the spread of resistance. … an
illustrative example of the evolution of multiple antibiotic resistance as a consequence of repeated …

[HTML][HTML] Inhibition of mutation and combating the evolution of antibiotic resistance

RT Cirz, JK Chin, DR Andes, V de Crécy-Lagard… - PLoS …, 2005 - journals.plos.org
… of drug resistance. In an initial effort to examine the role of induced mutation in the evolution
of antibiotic resistance, we have focused our studies on the synthetic antibiotic ciprofloxacin. …