… We provide evidence supporting that this small resistance variability strongly affects
evolutionary dynamics for nitrofurantoin, limits resistance development, and confines evolution to …

… We analyzed the evolution of resistance in Escherichia coli under selection with single drugs,
… We measured the drug resistance of these libraries using an automated robotic system (…

… Evolutionary biology has focused the lens through which we study drug resistance in
microbes, helping to create a language to describe the evolutionary relationship between …

… of the network of ARV-resistant strains (13). We calibrated the model… evolutionary dynamics,
from 1987 to 2008, of a network of ~4000 resistant strains, where each strain differed in drug …

… Attempts to disrupt the molecular mechanisms of resistance have generally been … evolutionary
dynamics of treatment-resistant cancer populations. We describe a variety of evolutionarily …

… Therefore, topics discussed in Part 2 of this review include evolutionary dynamics of clonal
… of clone–clone–stroma interactions for drug resistance. The ultimate goal of the future …

… “evolutionarily enlightened” cancer therapy. We suggest conceptualizing the evolutionary
dynamics of resistance … A key factor in the evolutionary dynamics of adaptation to any therapy (…

… the usefulness of drugs not only requires cost-… evolutionary dynamics of pathogen resistance.
Mathematical and computational models of population biology and evolutionary dynamics …

… Here we report the first comprehensive comparison of genome evolutionary dynamics in
multiple K. pneumoniae clones. We leveraged a curated collection of >2200 K. …

… required to predict the evolution of pathogens in response to drug pressure. Our results …
evolutionary dynamics, and illustrate how these feedbacks can be exploited to control resistance. …