… Thus, it may well be that the shift from hexamer storage to monomer storage was part of a
more general evolutionary shift in insulin function. In fact, since guinea pig glucagon also has …

… underlying molecular changes at the genomic level. Here, we combined an experimental
evolution … We show that a dramatic shift in the frequency of genetic variants, coupled with major …

… evolution of protein function attributable to convergent or parallel changes at the amino acid
level? The mutations that contribute to adaptive protein evolution … evolution at the molecular …

… that the rapid evolution of this RNA virus is caused by the high … substitutions (that do
not cause amino acid changes) … tors suggest that evolutionary shift of directional mutation …

… molecules, and we propose a conceptual framework for the study of functional shifts during
evolution … However, we will not understand the causes and consequences of evolutionary …

… mechanisms and evolutionary processes by which biological molecules diversified and to …
sufficient to recapitulate a 70,000-fold shift in hormone preference. Experimental biochemical …

… cases of convergent evolution at the molecular level, ranging from … convergence suggest
that molecular evolution is in some … further insights into the causes of genetic convergence and …

… evolutionary response of populations undergoing a shift in … preponderance of mutations
cause complete or partial loss … molecular evolution and on the ability to couple evolutionary …

… change following a host shift, we need to understand what causes virulence. Virulence is …
lower rates of molecular evolution [73,74] The physiological and molecular reasons why DCV …

… We used SPLATCHE to simulate DNA sequence diversity under different scenarios of range
contractions and range shifts. We report patterns of molecular diversity at different scales (…