… the mechanism of metal ions in promoting bone tissue growth… metal ions, and lists some
specific applications of metal ions … ions and analyzes the future research trend of metal ions in …

… to construct novel bioactive soft biomaterials by hybridizing metal ions and polymers at the
… -Mg, PGS has excellent biocompatibility, elasticity, and biodegradability and thus has been …

… We developed a new type of granular bioactive bone graft material with good biodegradability
as well as capacity for sustained release of bioactive ions (ie, Mg 2+ , Ca 2+ , Si 4+ ), by …

… linked to the release of metallic ions (Zn 2+ and Cu 2+ ) and hydroxide ions (which
increases the pH value). A previous study reported that Zn ions are considered to elicit effective …

… ions in the implantation site, which will cause cytotoxicity. Moreover, controlling the release
of bioactive ions can … Thus, the PLGA/Cu(I)@ZIF-8 scaffold has excellent antibacterial effects …

… The kinetics of hydrolysis of these materials depends not only on pH levels, ion concentrations,
and … Biodegradable polymers that have been extensively studied are excellent substrate …

… A suitable and sustained Zn ions release would be highly desirable for the biodegradable …
, for purposes such as corrosion controlling and bioactive improving. Up to now, a great variety …

… Herein, we designed a biodegradable monodispersed bioactive … excellent in vivo bone
repair ability in rat cranial defects. This work presents a distinctive strategy to design a bioactive …

… In this study, a multifunctional bioactive bone cement reinforced with the poly(citrate-silicon)
(PCS) nanospheres was developed for overcoming the limitation of PMMA bone cement (…

… also demonstrate excellent biocompatibility, controlled degradation, and specific bioactive
… At the same time, Zn promotes apoptosis of osteoclasts by modulating the Ca ion signaling …