Delayed metabolic dysfunction in myocardium following exertional heat stroke in mice
O Laitano, CK Garcia, AJ Mattingly… - The Journal of …, 2020 - Wiley Online Library
… chronic heart failure have compromised thermoregulation in heat (Cui et al. 2005; … heat
stroke. However, we hypothesize the reverse, that is, that the exposure to exertional heat stroke …
stroke. However, we hypothesize the reverse, that is, that the exposure to exertional heat stroke …
[HTML][HTML] Myocardial structure and functional alterations in a preclinical model of exertional heat stroke
CM Chao, LY Wang, CC Huang, WT Chang, LY Tang… - Life Sciences, 2023 - Elsevier
… damage (evidenced by increased plasma levels of both myocardial … myocardium structure
and function. A recent report showed that exposure to EHS in female mice, but not male mice, …
and function. A recent report showed that exposure to EHS in female mice, but not male mice, …
Long-term epigenetic and metabolomic changes in the mouse ventricular myocardium after exertional heat stroke
… to, or predict the developing stress-induced long-term … ventricular myocardium along with
resting mRNA expression and resting metabolomics after 30 days of recovery from EHS in mice …
resting mRNA expression and resting metabolomics after 30 days of recovery from EHS in mice …
A New Model of Exertional Heat Stroke in Male Mice Reveals Sustained Metabolic Dysfunction in the Myocardium
BJ Gambino, CK Garcia, MT Rua… - The FASEB …, 2022 - Wiley Online Library
… Exertional heat stroke (EHS) is a life threating condition that has grown in prevalence with
… in the ventricular myocardium (VM) after 14 days of recovery only in female mice. However, …
… in the ventricular myocardium (VM) after 14 days of recovery only in female mice. However, …
Delayed metabolic disturbances in the myocardium after exertional heat stroke: contrasting effects of exertion and thermal load
CK Garcia, BJ Gambino, GP Robinson… - Journal of Applied …, 2023 - journals.physiology.org
… Several years ago, in collaboration with US Army investigators, our laboratory 50 developed
a pre-clinical model of exertional heat stroke (EHS) in mice that simulates 51 most of the …
a pre-clinical model of exertional heat stroke (EHS) in mice that simulates 51 most of the …
Metabolic dysfunction in the myocardium three months after exertional heat stroke in mice
T Clanton, J Alzahrani, A Smuder, R Montalvo… - …, 2024 - journals.physiology.org
… In humans, exposure to heat stroke has proven to be a risk factor for … to exertional heat
stroke (EHS) would result in the development of similar long-term cardiac disease in mice. In this …
stroke (EHS) would result in the development of similar long-term cardiac disease in mice. In this …
Long‐term myocardial DNA methylation and metabolomic responses to exertional heat stroke in mice
… exertional heat stroke (EHS) can increase the risk of all-cause cardiovascular and systemic
disease and promote early mortality. Using a preclinical mouse … the ventricular myocardium (…
disease and promote early mortality. Using a preclinical mouse … the ventricular myocardium (…
Sex-dependent responses to exertional heat stroke in mice
CK Garcia, AJ Mattingly, GP Robinson… - Journal of Applied …, 2018 - journals.physiology.org
… susceptibilities to exertional heat injury or heat stroke. In this study we compared responses
of male and female adult mice to exertional heat stroke (EHS). All mice were instrumented …
of male and female adult mice to exertional heat stroke (EHS). All mice were instrumented …
Myocardial oxidative stress and inflammation emerges during recovery from exertional heat stroke in female but not male mice
CK Garcia, GP Robinson, AJ Mattingly… - The FASEB …, 2020 - Wiley Online Library
… Epidemiological reports have shown an association between heat stroke and … of exertional
heat stroke (EHS), we reported metabolic disturbances in the myocardium of female mice that …
heat stroke (EHS), we reported metabolic disturbances in the myocardium of female mice that …
An Exertional Heat Stroke Event Causes Hyperkalemia, Rhabdomyolysis, and Myocardial Autophagy Resulting in Long-Term Myocardial Fibrosis, Hypertrophy, and …
CM Chao, LY Wang, CC Huang, WT Chang… - … , and Myocardial … - papers.ssrn.com
… that exposure to EHS in female mice has the capacity to 417 … Myocardial dysfunction
characterized by elevated cardiac … 2 Exertional heat stroke onset induces myocardial injury and …
characterized by elevated cardiac … 2 Exertional heat stroke onset induces myocardial injury and …
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