Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPARα in the associated hypertrophy

S Ares-Carrasco, B Picatoste, E Camafeita… - … of Proteomics, 2012 - Elsevier
… In previous data, proteomic studies revealed alteration of the … In experimental diabetic
cardiomyopathy, a PPARα-agonist … the putative synergistic proteomes of chronic diabetes and …

Proteomics in diabetes research

T Sundsten, H Ortsäter - Molecular and Cellular Endocrinology, 2009 - Elsevier
… also been investigated using proteomic approaches. In this paper the field of diabetes
proteomics today will be reviewed. Findings from proteomic studies investigating pancreatic islets …

Proteomic studies in animal models of diabetes

S Resjö, K Berger, M Fex… - PROTEOMICS–Clinical …, 2008 - Wiley Online Library
… the workflow of a proteomics experiment. Before the actual proteomics experiment, the sam…
represents an important contribution to the field of proteomics in animal models of diabetes. …

Proteomic study on the new potential mechanism and biomarkers of diabetes

N Wang, S Zhang, F Zhu, Y Yang… - PROTEOMICS …, 2019 - Wiley Online Library
change with the stimulus of external environment, which makes proteomics a powerful
approach to study diabetes … average body weights were selected to perform the experiment. All …

Proteomics of the rat myocardium during development of type 2 diabetes mellitus reveals progressive alterations in major metabolic pathways

AV Edhager, JA Povlsen, B Løfgren… - Journal of Proteome …, 2018 - ACS Publications
diabetic fatty rat heart as T2DM develops using MS based proteomics. The prediabetic state
only induced minor pathway … The experimental work was approved by the Danish Animal …

Temporal transcriptomic and proteomic landscapes of deteriorating pancreatic islets in type 2 diabetic rats

J Hou, Z Li, W Zhong, Q Hao, L Lei, L Wang, D Zhao… - Diabetes, 2017 - Am Diabetes Assoc
… mRNA and protein expression changes of pancreatic islets in Goto-… and proteome data offer
a valuable resource for the diabetes … JH performed the proteomic experiments and MS data …

[HTML][HTML] The application of post-translational modification oriented serum proteomics to assess experimental diabetes with complications

HM Chen, LC Lee, KY Hu, WJ Tsai, C Huang, HJ Tsay… - PloS one, 2018 - journals.plos.org
Proteome analysis of serum from type 2 diabetics with … To circumvent the principal
barrier of serum proteomics, our … pathways related to type 2 diabetes pathogenesis. Type 2 …

Proteomic changes associated with diabetes in the BB-DP rat

DT Johnson, RA Harris, S French… - American Journal …, 2009 - journals.physiology.org
… Six sets of male rats were selected for proteomics experiments, all of which were killed at blood
… Fifteen millimolar Tris buffer, pH 8.5, was added to the lysis buffer for 2D gel experiments. …

Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus …

H Husi, T Van Agtmael, W Mullen… - Circulation …, 2014 - Am Heart Assoc
diabetes mellitus–induced key molecular changes in the vasculature. An integrative proteomic
… in the low-dose streptozotocin-induced diabetic mouse model (10 animals) was performed…

[HTML][HTML] Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice

M Leal-Julià, JJ Vilches, A Onieva, S Verdés… - Molecular …, 2022 - Elsevier
… Animal care and experimental procedures were approved by the Biosafety and the Ethical
… of diabetes to characterize the DRG and SCN proteome before morphometric changes were …