The importance of identifying and validating prognostic factors in oncology

S Halabi, K Owzar - Seminars in oncology, 2010 - Elsevier
experimental covariables to outcomes, is one of the major objectives in clinical research.
Historically, the impetus for the identification of prognostic factors … to prognostic factors rather …

[PDF][PDF] Prognostic role of tumor-infiltrating lymphocytes in gastric cancer: a meta-analysis and experimental validation

N Zhang, M Cao, Y Duan, H Bai, X Li… - Archives of Medical …, 2020 - termedia.pl
… of FOXP3+ T cell infiltration may not be recognized as a negative prognostic factor. These
results may provide some useful prognostic indicators for clinical application in gastric cancer. …

Identification and experimental validation of immune-associate lncRNAs for predicting prognosis in cervical cancer

J Ye, X Chen, W Lu - OncoTargets and therapy, 2021 - Taylor & Francis
… of these factors indicated that the immune-related lncRNA classifier was a reliable and
independent prognostic factor for OS ( Figure 10B ). This indicated the prognosis model had a …

Prognostic factors in patients with advanced cancer: a comparison of clinicopathological factors and the development of an inflammation-based prognostic system

BJ Laird, S Kaasa, DC McMillan, MT Fallon… - Clinical Cancer …, 2013 - AACR
… in advanced cancer (combining performance status and mGPS) is tested and then validated.
Experimental Design: Two international biobanks of patients with advanced cancer were …

Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma

M Zhou, H Zhao, Z Wang, L Cheng, L Yang… - Journal of experimental …, 2015 - Springer
… powerful prognostic factor than established laboratory prognostic … indicated that these four
prognostic lncRNAs may play … further experimental validation of these four prognostic lncRNAs …

Prognostic factor studies

M Schumacher, N Holländer, G Schwarzer… - Handbook of statistics …, 2005 - taylorfrancis.com
… In the 100 repetitions of our simulation experiment, 39 … Because the Nottingham Prognostic
Index has been validated in … We therefore attempted to validate the prognostic classification …

[HTML][HTML] MicroRNA profiling associated with non-small cell lung cancer: next generation sequencing detection, experimental validation, and prognostic value

S Gallach, E Jantus-Lewintre, S Calabuig-Fariñas… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… Furthermore, response to growth factor stimulus and cellular response to growth factor
stimulus GO terms were found enriched in this analysis. This fact is in concordance with the …

Why do so many prognostic factors fail to pan out?

SG Hilsenbeck, GM Clark, WL McGuire - Breast cancer research and …, 1992 - Springer
experiments were designed to mimic the characteristics of relapse-free survival data that
might be encountered in a prognostic factorvalidation sets, ad hoc adjustment factors, or other …

Is integrin subunit alpha 2 expression a prognostic factor for liver carcinoma? A validation experiment based on bioinformatics analysis

L Zhang, Y Huang, JJ Ling, W Zhuo, Z Yu, Y Luo… - Pathology & Oncology …, 2019 - Springer
… present validation research. However, the previous study failed to show ITGA2 as a prognostic
factor … was suggested to be an independent prognostic factor for liver cancer patients. The …

Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma

TM Mekhail, RM Abou-Jawde, G BouMerhi… - Journal of clinical …, 2005 - ascopubs.org
validated in different studies. We were able to validate Motzer’s data and find additional
prognostic factors (… involved) to also be independent prognostic factors in the survival of patients …