Exploratory analysis for a targeted patient population responsive to the metabotropic glutamate 2/3 receptor agonist pomaglumetad methionil in schizophrenia
BJ Kinon, BA Millen, L Zhang, DL McKinzie - Biological psychiatry, 2015 - Elsevier
… nonexposure to CNS drugs with prominent D2 receptor antagonist activity or 5-HT2A
receptor antagonist activity). Post hoc analyses were initially performed in patients in the HBBM …
receptor antagonist activity). Post hoc analyses were initially performed in patients in the HBBM …
Effects of a 5-HT7 receptor antagonist DR4004 on the exploratory behavior in a novel environment and on brain monoamine dynamics in mice
H Takeda, M Tsuji, H Ikoshi, T Yamada… - European journal of …, 2005 - Elsevier
… D2 receptor antagonist on the exploratory behaviors of mice in the hole-board test … reuptake
inhibitors and dopamine D2 receptor antagonist on the exploratory behaviors of mice in the …
inhibitors and dopamine D2 receptor antagonist on the exploratory behaviors of mice in the …
Effect of mineralocorticoid receptor antagonism and ACE Inhibition on angiotensin profiles in diabetic kidney disease: An exploratory study
JJ Kovarik, CC Kaltenecker, O Domenig, M Antlanger… - Diabetes Therapy, 2021 - Springer
… We hypothesize that mineralocorticoid receptor antagonists (MRA) on top of conventional
RAAS blockade change the angiotensin pattern resulting in cardio- and renoprotective effects. …
RAAS blockade change the angiotensin pattern resulting in cardio- and renoprotective effects. …
The effects of cholecystokinin A and B receptor antagonists, devazepide and L 365260, on citalopram-induced decrease of exploratory behaviour in rat
V Matto, J Harro, L Allikmets - Journal of physiology and …, 1996 - agro.icm.edu.pl
… , receptor subtype (5, 10, 30). In our second set of experiments, the CCK, receptor antagonist
… Contrary, the CCK, receptor antagonist L 365260 at the dose level of 10 mg/kg reversed …
… Contrary, the CCK, receptor antagonist L 365260 at the dose level of 10 mg/kg reversed …
Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long‐term potentiation, short‐term exploratory modulation and spatial memory in …
… administration of low doses of NMDA receptor antagonists, this being particularly evident for
… , therapeutically relevant doses of NMDA receptor antagonists do not block, and may even …
… , therapeutically relevant doses of NMDA receptor antagonists do not block, and may even …
Histamine‐2 receptor antagonists and risk of lung cancer in diabetic patients–an exploratory analysis
CL Hsu, CH Chang, JW Lin, LC Wu… - … and drug safety, 2013 - Wiley Online Library
… In conclusion, in the exploratory study, we demonstrated that a higher cumulative use of
H2RBs was associated with a reduced risk for non-small cell lung cancer in diabetic patients. …
H2RBs was associated with a reduced risk for non-small cell lung cancer in diabetic patients. …
A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients
… Secondary objectives were to test whether rhIL-1ra has biological activity, and to perform
an exploratory analysis of efficacy. The trial was conducted at an acute teaching hospital trust …
an exploratory analysis of efficacy. The trial was conducted at an acute teaching hospital trust …
Effects of antagonists at the NMDA receptor complex in two models of anxiety
A Plaznik, W Palejko, M Nazar, M Jessa - European …, 1994 - Elsevier
… anxiety (the open field exploratory behavior of non-habituated … (icv) significantly increased
exploratory activity in the central … -like action of NMDA receptor antagonists in mice and rats. …
exploratory activity in the central … -like action of NMDA receptor antagonists in mice and rats. …
The effects of cholecystokinin A and B receptor antagonists on exploratory behaviour in the elevated zero-maze in rat
V Matto, J Harro, L Allikmets - Neuropharmacology, 1997 - Elsevier
… effect of the CCK receptor antagonists on the exploratory behaviour of experimentally naive
… , the BDZ receptor inverse agonists FG 7142 and DMCM, and the BDZ receptor antagonist …
… , the BDZ receptor inverse agonists FG 7142 and DMCM, and the BDZ receptor antagonist …
Final safety and efficacy analysis of the specific endothelin A receptor antagonist zibotentan (ZD4054) in patients with metastatic castration‐resistant prostate cancer …
ND James, A Caty, H Payne, M Borre… - BJU …, 2010 - Wiley Online Library
… The results obtained in the present study support endothelin A receptor antagonism as
an approach for treating patients with CRPC. To confirm the survival signal observed in the …
an approach for treating patients with CRPC. To confirm the survival signal observed in the …
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