The spread of extended-spectrum β-lactamases (ESBLs) in nosocomial and community-acquired
enterobacteria is an important challenge for clinicians as the therapeutic options for …

… , clinical data on these infections in non-outbreak settings are limited.Little is known about the
prevalence of ESBLKP, their clinical significance and impact … and clinical characteristics of …

… , and clinical consequences of class A ESBLs in P. aeruginosa. … -spectrum TEM-type
enzymes may limit antibiotic selection of TEM- and SHV-type enzymes with an expanded spectrum …

… cephalosporin but susceptible to another, may in fact provide accurate results predictive of
clinical outcome. Because the clinical significance of ESBL-mediated resistance has not yet …

… This review discusses the recent findings (July 2008–January 2010) on extended-spectrum
β-lactamase (ESBL)-producing Escherichia coli, mainly focussed on the epidemiology and …

… The clinical impact of ESBL-PE colonization in the ICU was assessed from the rate of positive
clinical samples until hospital discharge, mortality rate and length of stay, and comparing …

… The successful worldwide spread of extended-spectrum β-lactamase (ESBL)-… the impact of
their genetic multidrug evolution on clinical aspects such as therapeutic selection. The clinical …

… The present review summarizes recent reports in the medical literature related to the clinical
significance of ESBL expression and describes strategies for the treatment of infections …

… Clinical significance and impact on mortality of extendedspectrum beta-lactamase-producing
Enterobacteriaceae isolates in nosocomial bacteremia. Scand J Infect Dis. 2001; 33:188-93…

… Clinical significance of β-lactamase induction and stable derepression in gram-negative …
Biochemical sequence analyses of GES-1, a novel class A extended-spectrum βlactamase, and …