… rise in infections caused by extended-spectrum β-lactamase (… infections, even when in vitro
activity to other β-lactams has … -carbapenem β-lactams for the treatment of ESBL infections …

… Because the enzyme was active against the expandedspectrum b-lactam … “extendedspectrum
b-lactamases” (ESBLs). To date, there are 1130 TEM-type and 150 SHV-type b-lactamases…

… Production of β-lactamase is the most frequent β-lactam … complex world of β-lactamases,
extended-spectrum β-lactamases (ESBLs… infections caused by extended-spectrum β-lactamase …

… active site of these β-lactamases. This extends the spectrum of β-lactam antibiotics susceptible
to … Carbapenems are the treatment of choice for serious infections due to ESBL-producing …

… mainly from the TEM or SHV types of β-lactamases, by point mutations in the parent enzymes
which did not possess extended-spectrum β-lactam substrate activity. The CTX-M type of …

… epidemiology of infections due to extended-spectrum β-lactamase-producing organisms. …
in the epidemiology of infections due to extended-spectrum β-lactamase-producing organisms. …

… as important causes of community-onset urinary tract infections (UTIs) and bloodstream
infections due to extended-spectrum β-lactamase (ESBL)-producing bacteria. Molecular …

Extended-spectrum β-lactamase (ESBL) producing gram-negative bacilli are a growing
concern in human medicine today. When producing these enzymes, organisms (mostly K. …

… the source and severity of infection and the susceptibility profile … decisions for treatment of
infections caused by MDR and … treatment of infections due to extended-spectrum-β-lactamase (…

… using broad spectrum antibiotics for specific infections like hospital or ventilator associated
pneumonia, blood stream infections, urinary tract infections and intra-abdominal infections. …