β-lactam and β-lactamase inhibitor combinations in the treatment of extended-spectrum β-lactamase producing Enterobacteriaceae: time for a reappraisal in the era of …

PNA Harris, PA Tambyah, DL Paterson - The Lancet Infectious …, 2015 - thelancet.com
… The spread of extended-spectrum β-lactamase (ESBL) genes in Enterobacteriaceae such …
ESBL producers might be susceptible to β-lactam-β-lactamase inhibitor (BLBLI) combination

β-Lactam/β-Lactam Inhibitor Combinations for the Treatment of Bacteremia Due to Extended-Spectrum β-Lactamase–Producing Escherichia coli: A Post Hoc Analysis …

…, Extended-Spectrum Beta-Lactamases … - Clinical Infectious …, 2012 - academic.oup.com
… are inhibited by β-lactamase inhibitors [1–3]. Although hyperproduction of β-lactamases or
… the activity of these compounds, β-lactam/β-lactam inhibitor combinations (BLBLI) such as …

… multinational, preregistered cohort study of β-lactam/β-lactamase inhibitor combinations for treatment of bloodstream infections due to extended-spectrum-β-lactamase …

B Gutiérrez-Gutiérrez, S Perez-Galera… - Antimicrobial agents …, 2016 - Am Soc Microbiol
… We investigated whether β-lactam/β-lactamase inhibitor (BLBLI) combinations are as
effective as carbapenems in the treatment of bloodstream infections (BSI) due to ESBL-E. A …

… with Fluoroquinolones or with β-Lactam-β-Lactamase Inhibitor Combinations Is a Risk Factor for Isolation of Extended-Spectrum-β-Lactamase-Producing Klebsiella …

KM Wener, V Schechner, HS Gold… - Antimicrobial agents …, 2010 - Am Soc Microbiol
… or to β-lactam-β-lactamase inhibitor combinations during hospitalization is a risk factor for
ESBL-producing Klebsiella infections, while broad-spectrum cephalosporins are predictive of …

Can We Really Use ß-Lactam/ß-Lactam Inhibitor Combinations for the Treatment of Infections Caused by Extended-Spectrum ß-Lactamase–Producing Bacteria?

F Perez, RA Bonomo - Clinical Infectious Diseases, 2012 - academic.oup.com
… colleagues asserts that the β-lactam/β-lactamase inhibitor (BLBLI) combinations piperacillin/…
due to Escherichia coli possessing extended-spectrum β-lactamases (ESBLs). The authors …

β-lactam/β-lactamase inhibitor combinations: an update

KHME Tehrani, NI Martin - Medchemcomm, 2018 - pubs.rsc.org
… in combination with the β-lactamase inhibitors covered in this review. The first generation
of β-lactamase inhibitors … Their findings reveal a broad spectrum synergistic effect against …

[HTML][HTML] … alone or in combination with a β-lactamase inhibitor and two aminoglycosides against Klebsiella pneumoniae harboring extended-spectrum β-lactamases

M Roussel-Delvallez, F Wallet, A Dao, V Marti… - Clinical microbiology …, 1998 - Elsevier
Objective To study the bactericidal activity of β-lactam antibiotics (imipenem, cefepime,
cefpirome) alone or in combination with a β-lactamase inhibitor (sulbactam) in the presence or …

Impact of acquired broad-spectrum β-lactamases on susceptibility to cefiderocol and newly developed β-lactam/β-lactamase inhibitor combinations in Escherichia coli …

L Poirel, JM Ortiz de la Rosa, M Sadek… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
… series of broad-spectrum β-lactamases on susceptibility to … the potential effect broad-spectrum
β-lactamases might have … of the different broad-spectrum β-lactamases on resistance to BL/…

Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population

PD Tamma, MV Villegas - Antimicrobial agents and …, 2017 - Am Soc Microbiol
β-Lactam/β-lactam inhibitor combinations for the treatment of bacteremia due to extended-spectrum
β-lactamase-producing Escherichia coli: a post hoc analysis of prospective cohorts. …

β-lactam/β-lactamase inhibitor combinations: from then to now

KA Toussaint, JC Gallagher - Annals of Pharmacotherapy, 2015 - journals.sagepub.com
… are new β-lactamase inhibitors that are being studied in combination with β-lactams. Clinical
and … β-Lactam antibiotics are a mainstay for the treatment of many infections. The addition of …