… β-lactamases. Horizontal gene transfer is the most common mechanism associated with the
spread of extended-spectrum β-lactam- … of ESBLs and carbapenemases have emerged with …

… the carbapenemases, a diverse group of b-lactamases that … lactamases: the IMP-type
carbapenemases and the VIM (Verona integron-encoded metallo-b-lactamase) carbapenemases…

… inactivate these compounds by hydrolyzing their β-lactam ring. Such resistance is caused …
broad-spectrum β-lactamases (BSBLs), the so-called extended-spectrum β-lactamases (ESBLs…

… extended-spectrum β-lactamases (ESBLs), AmpC β-lactamases, and carbapenemases of
… best for each type of carbapenemase and how to report positive carbapenemase tests to the …

… ‘broad spectrum’, when both reference substrates were hydrolysed at similar rates. Among
the broad-spectrum … The pragmatic reasons for separating carbapenemases from ESBLs are …

… extended-spectrum antibiotics has led to the appearance of extended spectrum β-lactamases
(ESBLs) enzymes, such as CTX and SHV enzymes, however not all SHV β-lactamase …

… Outbreaks of ESBL in nosocomial settings may be curtailed by restricting the use of broad-spectrum
cephalosporins. Switching to CPs or β-lactam/β-lactamase inhibitors (especially …

… β-lactamases belong to different functional and/or structural classes, they all certainly share
an extended spectrum of β-lactam … This probably reflects the fact that carbapenemases have …

… For extended-spectrum β-lactamase and AmpC producers, carbapenems are the drugs
of choice, but alternatives are needed because the rate of carbapenem resistance is rising. …

… Hence, the aim of this study was to determine the prevalence of ESBL- and
carbapenemase-producing Enterobacteriaceae among children suspected of septicemia and urinary …