Defining an extendedspectrum βlactamase

DM Livermore - Clinical Microbiology and Infection, 2008 - Wiley Online Library
… -broad-spectrum b-lactamase’, was first coined for derivatives of TEM and SHV enzymes …
Novel GES ⁄ IBC extended-spectrum b-lactamase variants with carbapenemase activity in clin…

[PDF][PDF] More extended-spectrum beta-lactamases

GA Jacoby, AA Medeiros - Antimicrobial agents and …, 1991 - Am Soc Microbiol
… TEM-related ,-lactamases, which consequently may contain … The pls of extendedspectrum
P-lactamases in the TEM family … the various extended-spectrum P-lactamases (56). The …

[PDF][PDF] Extended-spectrum beta-lactamases

A Philippon, R Labia, G Jacoby - Antimicrobial agents and …, 1989 - Am Soc Microbiol
… the substrate spectra of the enzymes. Hence, penicillins, cephalosporins, and other, B-lactam
to be virtually resistant to usual amounts of, B-lactamase could be developed. Some patho-…

Extended-spectrum β-lactamases: a clinical update

DL Paterson, RA Bonomo - Clinical microbiology reviews, 2005 - Am Soc Microbiol
… 2b β-lactamases (for example, TEM-1, TEM-2, and SHV-1); the e of 2be denotes that the β-lactamases
have an extended spectrum. … They are not able to hydrolyze extended-spectrum

Extended-spectrum β-lactamases

PJ Turner - Clinical Infectious Diseases, 2005 - academic.oup.com
… Because the enzyme was active against the expandedspectrum b-lactam … “extendedspectrum
b-lactamases” (ESBLs). To date, there are 1130 TEM-type and 150 SHV-type b-lactamases

Clinical significance of extended-spectrum beta-lactamases

JP Quinn - European Journal of Clinical Microbiology and …, 1994 - Springer
Extended-spectrum beta-lactamases (ESBLs) have now … , especially exposure to
extended-spectrum beta-lactam agents. … spread of extended-spectrum beta-lactamases among …

Extended-spectrum β-lactamase-producing organisms

ME Falagas, DE Karageorgopoulos - Journal of Hospital infection, 2009 - Elsevier
Extended-spectrum β-lactamases (ESBLs), which hydrolyse extended-spectrum … β-Lactam/β-lactamase
inhibitor combinations may be of value, but the supporting evidence …

Recent developments in β lactamases and extended spectrum β lactamases

JN Samaha-Kfoury, GF Araj - Bmj, 2003 - bmj.com
… group of βlactamases is the metallo lactamases, or class B lactamases. These use a divalent
… for detection of extended-spectrum beta-lactamases in multiresistant Escherichia coli and …

Animal reservoirs for extended spectrum βlactamase producers

A Carattoli - Clinical Microbiology and Infection, 2008 - Wiley Online Library
… Food-producing animals are the primary reservoir of zoonotic pathogens, and the
detection of extended spectrum b-lactamase (ESBL) producers among Escherichia coli and …

Extended-spectrum β-lactamase-producing Enterobacteriaceae: an emerging public-health concern

JDD Pitout, KB Laupland - The Lancet infectious diseases, 2008 - thelancet.com
… β lactamases are bacterial enzymes that inactivate β-lactam … One group of β lactamases,
extended-spectrum β lactamases … β-lactam antibiotics, including the expanded-spectrum (or third…